ArticleFrontiers in neurology2026
Association between the triglyceride-glucose index and functional outcome at discharge in patients receiving standardized treatment for atherosclerotic and cardioembolic stroke.
Article in Frontiers in neurology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
0 citing papers in PubMed.
No citing paper in PubMed yet.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Objective: The triglyceride-glucose (TyG) index is gaining considerable attention as an emerging marker of metabolic syndrome. The TyG index is strongly associated with atherosclerosis and cardiovascular disease development. However, the impact of the TyG index on the functional outcome at discharge of patients receiving standardized treatment and its variability in different types of stroke have not been fully elucidated. Method: Baseline data, neurological scale scores, and laboratory indicators were retrospectively collected from ischemic stroke patients at Lianyungang Second People's Hospital and Lianyungang First People's Hospital. Patients were categorized into good and poor functional outcome groups based on the modified Rankin Scale (mRS) score at discharge. A logistic regression model was used to evaluate the relationship between the TyG index and functional outcome at discharge of patients with atherosclerotic and cardioembolic stroke. Results: A total of 854 patients were included in the analysis, including 712 patients with large artery atherosclerotic (LAA) and 142 patients with cardioembolism (CE). Subgroup comparisons based on different discharge-level functional outcomes showed that the TyG index of the 187 patients in the poor functional outcome at discharge group was higher than that of patients in the good functional outcome group (8.98 vs. 8.69). The restricted cubic curve revealed a nonlinear association between the TyG index and discharge-level functional outcome among LAA stroke patients (for nonlinearity, Conclusion: The TyG index was identified as a risk factor for poor functional outcome at discharge in LAA stroke but was not correlated with the functional outcome at discharge of CE stroke. Considering the limited sample size and insufficient statistical power of the CE subgroup, this negative result should not be over-interpreted, and large-scale clinical studies are required to further explore the potential prognostic value of the TyG index in cardioembolic stroke.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.