Evidence map›Paper›PMID 42889116›Full record

ReviewFrontiers in robotics and AI2026

Human-centric digital twins in industry 5.0: technologies, applications, and future directions.

Sagheer Khan, Saifullah Tumrani, Nguyen Van Nam, Moataz Ahmed, Ashfaq Khan, Mushtaq Khan

Abstract readReview
In one paragraph

Review in Frontiers in robotics and AI, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Sagheer KhanSDAIA-KFUPM Joint Research Center for Artificial Intelligence, KFUPM, Dhahran, Saudi Arabia.
Saifullah TumraniSDAIA-KFUPM Joint Research Center for Artificial Intelligence, KFUPM, Dhahran, Saudi Arabia.
Nguyen Van NamInformation and Computer Science Department, King Fahd University of Petroleum & Minerals (KFUPM), Dhahran, Saudi Arabia.
Moataz AhmedSDAIA-KFUPM Joint Research Center for Artificial Intelligence, KFUPM, Dhahran, Saudi Arabia.
Ashfaq KhanSchool of Engineering and Built Environment, Sheffield Hallam University, Sheffield, United Kingdom.
Mushtaq KhanAdditive Manufacturing Research and Innovation Center (AMRIC), Mechanical Engineering Department, College of Engineering, Prince Mohammad Bin Fahd University, Al Khobar, Saudi Arabia.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Industry 5.0 (I5.0) emphasizes industrial technologies that are human-centric, sustainable, and resilient. Human-Centric Digital Twins (HCDTs) support this transition by integrating worker data with robots, machines, tasks, and industrial environments. However, the relevant research remains fragmented across human modelling, Human-Robot Collaboration, Artificial Intelligence (AI), simulation, and Digital Twin (DT) research. Moreover, systems that use human data or adaptive automation are often described as human-centric without demonstrating measurable benefits to workers. This review addresses these limitations by distinguishing HCDTs from conventional human models, Human DTs, and collaborative robotic systems. It critically examines human-focused sensing, multi-modal data integration, biomechanical modelling, intention and motion prediction, robotic simulation, optimization, reinforcement learning, immersive interfaces, industrial connectivity, and data governance. Based on this analysis, a literature-derived conceptual framework is proposed that connects sensing, integration, human modelling, analytics, simulation, decision-making, adaptation, human interaction, and governance. The framework organizes the functional requirements of HCDTs and is intended to inform future system design and comparison; its practical applicability and effectiveness require further validation. The review argues that HCDTs must extend beyond worker monitoring and productivity maximization: human data should inform industrial decisions that produce measurable improvements in safety, ergonomics, wellbeing, autonomy, accessibility, or skill development. Such systems should also uphold privacy, transparency, uncertainty awareness, explainability, and appropriate human authority. By linking technological capabilities to explicit worker outcomes, this synthesis enables researchers and engineers to assess the human-centeredness of HCDT implementations and supports the development of trustworthy systems for I5.0.

Indexed as

adaptive roboticshuman-centric digital twinhuman intention predictionhuman-robot collaborationhuman sensingindustry 5.0

Identifiers

PMID42889116
PMCPMC13668560

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.