Evidence map›Paper›PMID 42889019›Full record

ReviewFood science & nutrition2026

Postbiotics Unveiled: The Next Emerging Trend in Functional Foods.

Zoha Wahid, Abdul Momin Rizwan Ahmad, Farheen Zulfiqar, Syed Hassan Bin Usman Shah, Nilab Mohammadi

Abstract readReview
In one paragraph

Review in Food science & nutrition, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Zoha WahidDepartment of Human Nutrition and Dietetics NUST School of Health Sciences, National University of Sciences & Technology (NUST) Islamabad Pakistan.
Abdul Momin Rizwan AhmadDepartment of Human Nutrition and Dietetics NUST School of Health Sciences, National University of Sciences & Technology (NUST) Islamabad Pakistan.ORCID https://orcid.org/0000-0003-3499-902X
Farheen ZulfiqarDepartment of Food Science and Human Nutrition University of Veterinary and Animal Sciences Lahore Pakistan.ORCID https://orcid.org/0000-0002-0509-9519
Syed Hassan Bin Usman ShahDepartment of Public Health PRIME Consulting Islamabad Pakistan.
Nilab MohammadiDepartment of Curative Medicine Ghalib University Herat Afghanistan.ORCID https://orcid.org/0009-0003-6376-0007

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The global population is expected to reach 9.7 billion by 2050, with demand for food increasing by up to 56%. Postbiotics are a safe and reliable substitute for probiotics, which are described as preparations of non-viable bacteria and/or their metabolic byproducts. Data for this narrative review was collected using Goggle scholar and PubMed from 2006 to 2026. Major bioactive compounds such as short-chain fatty acids, peptides, polysaccharides, vitamins, and cell fragments contribute to immunomodulatory, antioxidant, metabolic, and gut-brain axis effects. Preclinical and clinical research shows that they can improve insulin sensitivity, control cytokine signaling, strengthen epithelial barrier integrity, and protect against obesity, type 2 diabetes mellitus, and depression. Postbiotics have also been found to improve mineral absorption and folate synthesis, and possess anti-sarcopenic actions. Several commercial products are available because of their health benefits. Thus, postbiotics are a revolutionary development in microbiome-based treatments; however, to completely understand their therapeutic potential, it is necessary to standardize, achieve mechanistic clarity, and ensure regulatory alignment.

Indexed as

antimicrobial propertiesbioactive compoundsfunctional foodsimmunomodulatory propertiespostbioticsshort‐chain fatty acids

Identifiers

PMID42889019
PMCPMC13668483

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.