Evidence map›Paper›PMID 42888584›Full record

ArticleMedicine2026

Deaths involving chronic obstructive pulmonary disease and cardiac arrest in older US adults, 1999-2023: A retrospective cross-sectional study.

Shahid Khan, Jawad Zafar Mayo, Dina Mohammed, Muhammad Aamer, Priya Goyal, Muhammad Husnain Ahmad, Abdullah Raza Rashid, Humza Saeed

Abstract read
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Article in Medicine, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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1 · What the graph read from it

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2 · The registry

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3 · Its place in the literature

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4 · The record

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5 · Who and what money

Authors and funding

8 authors.

Shahid KhanDepartment of Internal Medicine, Saidu Medical College, Swat, Pakistan.
Jawad Zafar MayoDepartment of Internal Medicine, Rawalpindi Medical University, Rawalpindi, Pakistan.
Dina MohammedDepartment of Internal Medicine, School of Medicine, The University of Jordan, Amman, Jordan.
Muhammad AamerDepartment of Internal Medicine, Faisalabad Medical University, Faisalabad, Pakistan.
Priya GoyalDepartment of Internal Medicine, Dayanand Medical College and Hospital, Ludhiana, India.
Muhammad Husnain AhmadDepartment of Internal Medicine, Tentishev Satkynbai Memorial Asian Medical Institute, Kant, Kyrgyzstan.ORCID 0009-0006-5248-0749
Abdullah Raza RashidDepartment of Internal Medicine, Rawalpindi Medical University, Rawalpindi, Pakistan.
Humza SaeedDepartment of Internal Medicine, Rawalpindi Medical University, Rawalpindi, Pakistan.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

National long-term trends and disparities in deaths in which both chronic obstructive pulmonary disease (COPD) and cardiac arrest are recorded on death certificates are not well characterized. We used CDC WONDER Multiple Cause of Death data (1999-2023) to identify US adults aged ≥ 65 years whose death certificates listed both COPD (ICD-10 J41-J44) and cardiac arrest (I46) as underlying or contributing causes. Age-adjusted mortality rates (AAMRs) were stratified by sex, race/ethnicity, region, and urbanization; the urbanization analysis was limited to 1999 to 2020 because those data were not available after 2020. Trends were analyzed using annual percentage changes (APCs) with 95% confidence intervals (CIs); P < .05 was considered statistically significant. Among 7,18,280 deaths involving concurrent coding of COPD and cardiac arrest, AAMRs declined from 86.4 in 1999 to 52.5 in 2023. A significant decrease occurred from 1999 to 2006 (APC: -2.87; P = .01), followed by a plateau and a further decline from 2021 to 2023 (APC: -4.77; P < .001). Older men exhibited higher AAMRs than older women (86.8 vs 55.2). Non-Hispanic (NH) White individuals had the highest mortality (69.7), followed by NH Black/African American (64.3) and Hispanic/Latino (60.7) populations. The West region reported the highest AAMR (98.9). During 1999 to 2020, nonmetropolitan residents had higher AAMRs than metropolitan residents (70.8 vs 67.9). Population-level mortality records involving both COPD and cardiac arrest declined overall but remained heterogeneous across demographic and geographic strata. These findings describe concurrent coding on death certificates and do not establish that COPD increases the risk of cardiac arrest or causes the observed deaths.

Indexed as

Heart ArrestPulmonary Disease, Chronic ObstructiveAgedAged, 80 and overBlack or African AmericanCause of DeathCross-Sectional StudiesDeath CertificatesFemaleHispanic or LatinoHumansMaleRetrospective StudiesUnited StatesWhitecardiac arrestchronic obstructive pulmonary disease (COPD)health disparitiesmortalityolder adults

Identifiers

PMID42888584
PMCPMC13681117

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.