Evidence map›Paper›PMID 42888536›Full record

ArticleMedicine2026

Acute colonic variceal bleeding treated with coil-assisted retrograde transvenous obliteration following atezolizumab-bevacizumab therapy for advanced hepatocellular carcinoma: A case report.

Sung Eun Park, Hyeon Uk Kwon, Sa Hong Jo, Sung Gong Lim, Ji Yoon Kwak, Ji Hee Han, Hankyu Jeon, Ra Ri Cha, Jae Min Lee, Hyun Jin Kim and 1 more

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PubMed Full text at PMC Publisher
In one paragraph

Article in Medicine, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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3 · Its place in the literature

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4 · The record

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5 · Who and what money

Authors and funding

11 authors.

Sung Eun ParkDepartment of Radiology, Gyeongsang National University School of Medicine and Gyeongsang National University Changwon Hospital, Changwon, Republic of Korea.
Hyeon Uk KwonInstitute of Medical Sciences, Gyeongsang National University, Jinju, Republic of Korea.
Sa Hong JoDepartment of Radiology, Gyeongsang National University School of Medicine and Gyeongsang National University Changwon Hospital, Changwon, Republic of Korea.
Sung Gong LimDepartment of Radiology, Gyeongsang National University School of Medicine and Gyeongsang National University Changwon Hospital, Changwon, Republic of Korea.
Ji Yoon KwakInstitute of Medical Sciences, Gyeongsang National University, Jinju, Republic of Korea.
Ji Hee HanInstitute of Medical Sciences, Gyeongsang National University, Jinju, Republic of Korea.
Hankyu JeonInstitute of Medical Sciences, Gyeongsang National University, Jinju, Republic of Korea.
Ra Ri ChaInstitute of Medical Sciences, Gyeongsang National University, Jinju, Republic of Korea.
Jae Min LeeInstitute of Medical Sciences, Gyeongsang National University, Jinju, Republic of Korea.
Hyun Jin KimInstitute of Medical Sciences, Gyeongsang National University, Jinju, Republic of Korea.
Sang Soo LeeInstitute of Medical Sciences, Gyeongsang National University, Jinju, Republic of Korea.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

rationaleColonic variceal bleeding is a rare but potentially life-threatening manifestation of portal hypertension. Bevacizumab therapy is associated with an increased risk of variceal bleeding, but bleeding from ectopic varices is less well recognized. PATIENT CONCERNS: A 66-year-old man with alcohol-related cirrhosis and advanced hepatocellular carcinoma developed hematochezia on the day following the initiation of atezolizumab plus bevacizumab therapy. DIAGNOSES: Acute ascending colonic variceal bleeding in the setting of portal hypertension and portal vein thrombosis.

interventionsCoil-assisted retrograde transvenous obliteration (CARTO) was performed via the right common femoral vein. The portocolonic shunt was embolized using detachable coils and gelfoam slurry. OUTCOMES: Hematochezia ceased immediately after the procedure, and the patient remained hemodynamically stable without further transfusion. Follow-up computed tomography confirmed successful embolization of the variceal complex without residual shunt. LESSONS: CARTO may be an effective treatment option for colonic variceal bleeding, particularly in patients with portal vein thrombosis or complex portosystemic shunts. Clinicians should remain aware of the potential for bleeding from ectopic varices in patients receiving bevacizumab-based therapy.

Indexed as

Antibodies, Monoclonal, HumanizedBevacizumabCarcinoma, HepatocellularEmbolization, TherapeuticEsophageal and Gastric VaricesGastrointestinal HemorrhageLiver NeoplasmsAgedHumansHypertension, PortalMaleAntibodies, Monoclonal, HumanizedatezolizumabBevacizumabatezolizumabbevacizumabcase reportcoil-assisted retrograde transvenous obliterationcolonic variceal bleedinghepatocellular carcinoma

Identifiers

PMID42888536
PMCPMC13680955

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.