ArticlePhysiological reports2026
Is cardiovascular autonomic control during the day-to-night transition dependent on dim light melatonin onset? An exploratory analysis in healthy adults.
Article in Physiological reports, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
0 citing papers in PubMed.
No citing paper in PubMed yet.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors.
Funding
Abstract
We tested whether dim-light melatonin onset (DLMO) is time-aligned with the transition between biological day into night in cardiovascular autonomic control (CV onset time). We studied 10 healthy adults (4 females, age 25 ± SD 2 years) under an ultra-short semi-constant routine protocol (<8lux). Participants remained seated for 7 h until 1 h after their habitual bedtime. We collected saliva samples every 30 min and recorded R-R intervals and beat-to-beat blood pressure every hour. DLMO was defined as the interpolated time for melatonin increase over 3 pg/mL. Phase angle was defined as the time difference between DLMO and the midpoint of self-reported sleep as a measure of the alignment between sleep-wake patterns and biological circadian rhythms. CV onset time was defined using a segmental (piecewise) analysis to identify the inflection point (X
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.