Evidence map›Paper›PMID 42888404›Full record

ArticleBMC oral health2026

Adjunctive effect of dentifrices on the durability of in-office desensitizing treatment under erosive-abrasive conditions.

João Felipe Besegato, Leonardo Urbieta Portillo, Joissi Ferrari Zaniboni, Bárbara Dias Rigo, Andrea Freire, Éverton do Nascimento Alencar, Regina Guenka Palma-Dibb, Fernanda de Souza E Silva Ramos

Abstract read
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In one paragraph

Article in BMC oral health, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

João Felipe BesegatoSchool of Dentistry, Federal University of Mato Grosso do Sul (UFMS), Campo Grande, MS, Brazil. joao.besegato@ufms.br.ORCID http://orcid.org/0000-0001-8747-779X
Leonardo Urbieta PortilloSchool of Dentistry, Federal University of Mato Grosso do Sul (UFMS), Campo Grande, MS, Brazil.ORCID http://orcid.org/0009-0006-2866-2753
Joissi Ferrari ZaniboniDepartment of Restorative Dentistry, School of Dentistry of Ribeirão Preto (FORP), University of São Paulo (USP), Ribeirão Preto, SP, Brazil.ORCID http://orcid.org/0000-0003-0172-9891
Bárbara Dias RigoSchool of Dentistry, Federal University of Mato Grosso do Sul (UFMS), Campo Grande, MS, Brazil.ORCID http://orcid.org/0000-0002-4320-8253
Andrea FreireSchool of Dentistry, Federal University of Mato Grosso do Sul (UFMS), Campo Grande, MS, Brazil.ORCID http://orcid.org/0000-0002-1741-5857
Éverton do Nascimento AlencarLaboratory of Micro and Nanostructured Systems (LASMINano), College of Pharmaceutical Sciences, Food and Nutrition, Federal University of Mato Grosso do Sul (UFMS), Campo Grande, MS, Brazil.ORCID http://orcid.org/0000-0002-6148-6804
Regina Guenka Palma-DibbDepartment of Restorative Dentistry, School of Dentistry of Ribeirão Preto (FORP), University of São Paulo (USP), Ribeirão Preto, SP, Brazil.ORCID http://orcid.org/0000-0002-3247-0248
Fernanda de Souza E Silva RamosSchool of Dentistry, Federal University of Mato Grosso do Sul (UFMS), Campo Grande, MS, Brazil.ORCID http://orcid.org/0000-0003-2222-2424

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundThis study evaluated the effects of dentifrices on dentin permeability, surface roughness, dentinal tubule occlusion, and dentin chemical composition after in-office desensitizing treatment and an erosive-abrasive challenge.

methodsHuman dentin specimens were treated with fluoride varnish and randomly allocated to five groups according to dentifrice used: fluoride-free (WF), sodium fluoride (NaF), fluorocalcium phosphosilicate (FCPS), arginine + calcium carbonate (AC), and NovaMin

resultsFluoride varnish reduced dentin permeability in all groups (T1 vs. T0; p < 0.05). After erosive-abrasive challenge, permeability increased in all groups except FCPS. No differences among dentifrices were observed for permeability (P > 0.05) or surface roughness (P ≥ 0.33). Morphological analysis showed lower tubule number, area, and perimeter in FCPS and NM groups (P < 0.05). Qualitative FTIR suggested greater preservation of phosphate-related bands in FCPS and NM; however, no differences were observed in the phosphate-to-amide I ratio (P = 0.72).

conclusionsWithin the limitations of this in vitro study, dentifrices influenced the durability of in-office desensitizing treatment under erosive-abrasive conditions. FCPS demonstrated greater stability over time, while FCPS and NovaMin

Indexed as

DentifricesDentinDentin Desensitizing AgentsDentin PermeabilityDentin SensitivityTooth AbrasionTooth ErosionArginineCalcium CarbonateCalcium CompoundsFluorides, TopicalFluoride TreatmentGlassHumansIn Vitro TechniquesPhosphorus CompoundsArginineCalcium CarbonateCalcium CompoundsDentifricesDentin Desensitizing AgentsFluorides, TopicalNovaMinPhosphorus CompoundsSilicatesSodium CompoundsSodium FluorideDentifricesDentin permeabilityDentin sensitivityTooth abrasionTooth erosion

Identifiers

PMID42888404

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.