Evidence map›Paper›PMID 42888331›Full record

ArticleClinical oral investigations2026

An oxygen-releasing mouthwash shows species-dependent antibacterial and antibiofilm activity against periodontal pathogens.

Fatemah M AlAhmari, Rhodanne Nicole A Lambarte, Terrence S Sumague, Mary Grace B Vigilla, Marwa Y Shaheen, Sumaiah Ajlan, Lamees Alssum, Amani M Basudan, Abdurahman A Niazy

Abstract read
PubMed Publisher
In one paragraph

Article in Clinical oral investigations, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Fatemah M AlAhmariDepartment of Periodontics and Community Dentistry, College of Dentistry, King Saud University, Riyadh, Kingdom of Saudi Arabia. falahmari@ksu.edu.sa.ORCID http://orcid.org/0000-0001-5541-5252
Rhodanne Nicole A LambarteMolecular and Cell Biology Laboratory, Prince Naif bin AbdulAziz Health Research Center, King Saud University Medical City, King Saud University, Riyadh, Kingdom of Saudi Arabia.ORCID http://orcid.org/0000-0001-7978-3674
Terrence S SumagueMolecular and Cell Biology Laboratory, Prince Naif bin AbdulAziz Health Research Center, King Saud University Medical City, King Saud University, Riyadh, Kingdom of Saudi Arabia.ORCID http://orcid.org/0000-0001-5367-9967
Mary Grace B VigillaMolecular and Cell Biology Laboratory, College of Dentistry, King Saud University, Riyadh, Kingdom of Saudi Arabia.ORCID http://orcid.org/0000-0002-5657-2345
Marwa Y ShaheenDepartment of Periodontics and Community Dentistry, College of Dentistry, King Saud University, Riyadh, Kingdom of Saudi Arabia.ORCID http://orcid.org/0000-0001-6638-0075
Sumaiah AjlanDepartment of Periodontics and Community Dentistry, College of Dentistry, King Saud University, Riyadh, Kingdom of Saudi Arabia.ORCID http://orcid.org/0000-0003-2564-7970
Lamees AlssumDepartment of Periodontics and Community Dentistry, College of Dentistry, King Saud University, Riyadh, Kingdom of Saudi Arabia.ORCID http://orcid.org/0000-0002-7462-070X
Amani M BasudanDepartment of Periodontics and Community Dentistry, College of Dentistry, King Saud University, Riyadh, Kingdom of Saudi Arabia.ORCID http://orcid.org/0000-0002-3577-2161
Abdurahman A NiazyDepartment of Oral Medicine and Diagnostic Sciences, College of Dentistry, King Saud University, Riyadh, Kingdom of Saudi Arabia.ORCID http://orcid.org/0000-0003-0493-3601

Funding

King Saud University ORF-2026-2076
6 · The paper itself

Abstract

objectivesThis study evaluated whether an oxygen-releasing mouthwash formulation (O MATERIALS AND

methodsMinimum inhibitory concentrations (MICs) were determined using a resazurin-based broth microdilution, and minimum bactericidal concentration (MBC) by agar subculture. Agar diffusion assessed growth inhibition. Biofilm biomass was quantified using crystal violet staining, while pre-formed biofilm structure and membrane integrity were examined by confocal laser scanning microscopy (CLSM). Quantitative PCR assessed adhesion-, toxin-, oxidative-stress-, and iron-associated genes. Molecular docking used sodium perborate as a representative oxygen-releasing constituent.

resultsO

conclusionsO CLINICAL RELEVANCE: O

Indexed as

Aggregatibacter actinomycetemcomitansAnti-Bacterial AgentsBiofilmsMouthwashesOxygenPrevotella intermediaHumansMicrobial Sensitivity TestsMicroscopy, ConfocalAnti-Bacterial AgentsMouthwashesOxygenAggregatibacter actinomycetemcomitansBiofilmsChlorhexidineMouthwashesPeriodontitisPrevotella intermedia

Identifiers

PMID42888331

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.