Evidence map›Paper›PMID 42887898›Full record

ArticleGeriatrics & gerontology international2026

Beyond the Rankin Scale: A Patient-Centered Score for Meaningful Recovery After Mechanical Thrombectomy in Older Adults With Pre-Stroke Disability.

Hiroyasu Inoue, Masahiro Oomura, Yoshitaka Nakamura, Yusuke Nishikawa, Yuto Uchida, Shoya Kusui, Atsuhito Taishaku, Yoshiro Nozaki, Tomoyasu Yamanaka, Teishiki Shibata and 9 more

Abstract read
In one paragraph

Article in Geriatrics & gerontology international, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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0citing papers in PubMed
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1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

19 authors.

Hiroyasu InoueDepartment of Neurology, Nagoya City University Graduate School of Medical Sciences and Medical School, Nagoya, Aichi, Japan.ORCID https://orcid.org/0000-0003-3055-0057
Masahiro OomuraDepartment of Neurology, Nagoya City University Graduate School of Medical Sciences and Medical School, Nagoya, Aichi, Japan.ORCID https://orcid.org/0000-0002-8949-008X
Yoshitaka NakamuraDepartment of Neurology, Nagoya City University Graduate School of Medical Sciences and Medical School, Nagoya, Aichi, Japan.ORCID https://orcid.org/0009-0009-2557-4813
Yusuke NishikawaDepartment of Neurosurgery, Nagoya City University Graduate School of Medical Sciences and Medical School, Nagoya, Aichi, Japan.
Yuto UchidaDepartment of Neurology, Nagoya City University Graduate School of Medical Sciences and Medical School, Nagoya, Aichi, Japan.ORCID https://orcid.org/0000-0002-6521-0784
Shoya KusuiDepartment of Neurosurgery, Nagoya City University Graduate School of Medical Sciences and Medical School, Nagoya, Aichi, Japan.
Atsuhito TaishakuDepartment of Neurosurgery, Nagoya City University Graduate School of Medical Sciences and Medical School, Nagoya, Aichi, Japan.ORCID https://orcid.org/0009-0000-8061-8916
Yoshiro NozakiDepartment of Neurosurgery, Nagoya City University Graduate School of Medical Sciences and Medical School, Nagoya, Aichi, Japan.
Tomoyasu YamanakaDepartment of Neurosurgery, Nagoya City University Graduate School of Medical Sciences and Medical School, Nagoya, Aichi, Japan.
Teishiki ShibataDepartment of Neurosurgery, Nagoya City University Graduate School of Medical Sciences and Medical School, Nagoya, Aichi, Japan.
Yasuhide InoueDepartment of Neurosurgery, Nagoya City University Graduate School of Medical Sciences and Medical School, Nagoya, Aichi, Japan.
Yoko TaniguchiDepartment of Neurology, Nagoya City University Graduate School of Medical Sciences and Medical School, Nagoya, Aichi, Japan.ORCID https://orcid.org/0009-0000-0747-9569
Yuta MadokoroDepartment of Neurology, Nagoya City University Graduate School of Medical Sciences and Medical School, Nagoya, Aichi, Japan.ORCID https://orcid.org/0000-0002-0228-3898
Toyohiro SatoDepartment of Neurology, Nagoya City University Graduate School of Medical Sciences and Medical School, Nagoya, Aichi, Japan.ORCID https://orcid.org/0000-0002-1888-5279
Teppei FujiokaDepartment of Neurology, Nagoya City University Graduate School of Medical Sciences and Medical School, Nagoya, Aichi, Japan.
Masayuki MizunoDepartment of Neurology, Nagoya City University Graduate School of Medical Sciences and Medical School, Nagoya, Aichi, Japan.ORCID https://orcid.org/0000-0002-9530-5960
Shoji KawashimaDepartment of Neurology, Nagoya City University Graduate School of Medical Sciences and Medical School, Nagoya, Aichi, Japan.
Mitsuhito MaseDepartment of Neurosurgery, Nagoya City University Graduate School of Medical Sciences and Medical School, Nagoya, Aichi, Japan.
Noriyuki MatsukawaDepartment of Neurology, Nagoya City University Graduate School of Medical Sciences and Medical School, Nagoya, Aichi, Japan.ORCID https://orcid.org/0000-0002-6638-4516

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

aimThe benefit of mechanical thrombectomy (MT) for acute ischemic stroke in patients with pre-stroke moderate-to-severe disability is difficult to evaluate using the modified Rankin Scale (mRS) alone. We developed and evaluated the SMILE-Stroke score as a patient-centered outcome measure.

methodsWe conducted a retrospective cohort study of 31 patients with pre-stroke mRS scores of 3-5 who underwent MT. The 10-point SMILE-Stroke score, comprising Speech, Mobility, Ingestion, Lavatory, and Engagement domains, was assessed at discharge; a score ≥ 4 was prespecified as favorable. Interrater reliability, convergent validity with the Barthel Index, associations with discharge disposition and mRS, and pre-stroke SMILE-Stroke scores were evaluated.

resultsTwelve patients (38.7%) achieved a favorable SMILE-Stroke outcome. Interrater reliability was excellent for the total score (single-rater intraclass correlation coefficient = 0.957) and dichotomized outcome (Fleiss' κ = 0.863). The score correlated strongly with the discharge Barthel Index (Spearman's ρ = 0.86, p < 0.001) and showed a graded association with discharge disposition (Kruskal-Wallis p = 0.0012). For distinguishing discharge to home/original residence or rehabilitation hospital from long-term care hospital or death, the SMILE-Stroke score yielded an AUC of 0.82. Notably, 6 of 19 patients (31.6%) with 90-day mRS scores of 4-5 achieved a favorable SMILE-Stroke outcome.

conclusionsThe SMILE-Stroke score was feasible, reproducible, and associated with established functional and discharge outcomes in selected MT-treated patients with pre-stroke disability. It may complement the mRS by identifying preserved or regained patient-centered functional domains within poor mRS categories.

Indexed as

Disability EvaluationIschemic StrokeRecovery of FunctionStrokeStroke RehabilitationThrombectomyAgedAged, 80 and overFemaleHumansMaleReproducibility of ResultsRetrospective StudiesTreatment Outcomeacute ischemic strokemechanical thrombectomyoldest‐oldpre‐stroke disabilityquality of life

Identifiers

PMID42887898
PMCPMC13675113

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.