Evidence map›Paper›PMID 42886410›Full record

ReviewIntensive care medicine experimental2026

Mechanical ventilation-associated AKI: toward a multimodal and kidney-protective ventilatory framework.

Ying Gao, Yipeng Fang, Silvia De Rosa, Michele Salvagno, Lina Zhao, Keliang Xie, Fabio Silvio Taccone

Abstract readReview
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In one paragraph

Review in Intensive care medicine experimental, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Ying Gao *Department of Critical Care Medicine, Tianjin Medical University General Hospital, Tianjin, China.
Yipeng Fang *Department of Critical Care Medicine, Tianjin Medical University General Hospital, Tianjin, China.
Silvia De RosaCentre for Medical Sciences-CISMed, University of Trento, Trento, 38122, Italy.
Michele SalvagnoDepartment of Intensive Care, Hôpital Universitaire de Bruxelles (HUB), Université Libre de Bruxelles, Brussels, Belgium.
Lina ZhaoDepartment of Critical Care Medicine, Tianjin Medical University General Hospital, Tianjin, China.
Keliang XieDepartment of Critical Care Medicine, Tianjin Medical University General Hospital, Tianjin, China. xiekeliang2009@hotmail.com.
Fabio Silvio TacconeDepartment of Intensive Care, Erasme University Hospital - Université Libre de Bruxelles, Route de Lennik 808, Brussels, 1070, Belgium. ftaccone@ulb.ac.be.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Mechanical ventilation-associated acute kidney injury (AKI) represents a complex manifestation of lung-kidney cross-talk driven by hemodynamic alterations, neurohumoral activation, systemic inflammation and disturbances in gas exchange and acid-base homeostasis. Beyond static ventilatory settings, increasing evidence suggests that dynamic fluctuations in airway and perfusion parameters, including static driving pressure (ΔP), positive end-expiratory pressure (PEEP), mean airway pressure (P

Indexed as

Acute kidney injuryLung–kidney cross talkMechanical ventilationRenal perfusionVentilation parameters

Identifiers

PMID42886410

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.