Evidence map›Paper›PMID 42886038›Full record

ArticleJournal of human immunity2027

Higher serum sCD14 is an independent biomarker for porto-sinusoidal vascular disease risk in CVID.

Laure Delaval, Karim Dorgham, Jehane Fadlallah, Emilie Corvilain, Pierre-Emmanuel Rautou, Eric Oksenhendler, Claire Fieschi, Guy Gorochov, Marion Malphettes

Abstract read
PubMed Publisher
In one paragraph

Article in Journal of human immunity, 2027. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Laure DelavalSorbonne Université, Inserm, Centre D'Immunologie et des Maladies Infectieuses , Paris, France.ORCID 0000-0002-8340-7193
Karim DorghamSorbonne Université, Inserm, Centre D'Immunologie et des Maladies Infectieuses , Paris, France.ORCID 0000-0001-9539-3203
Jehane FadlallahNational Reference Center for Adult Primary Immunodefiencies, CEREDIH, Hôpital Saint-Louis, Université Paris-Cité , Paris, France.ORCID 0000-0003-3064-9401
Emilie CorvilainNational Reference Center for Adult Primary Immunodefiencies, CEREDIH, Hôpital Saint-Louis, Université Paris-Cité , Paris, France.ORCID 0009-0000-4257-4051
Pierre-Emmanuel RautouUniversité Paris-Cité, Inserm, Centre de Recherche sur L'inflammation, UMR 1149 , Paris, France.ORCID 0000-0001-9567-1859
Eric OksenhendlerNational Reference Center for Adult Primary Immunodefiencies, CEREDIH, Hôpital Saint-Louis, Université Paris-Cité , Paris, France.ORCID 0000-0001-8588-7138
Claire FieschiNational Reference Center for Adult Primary Immunodefiencies, CEREDIH, Hôpital Saint-Louis, Université Paris-Cité , Paris, France.ORCID 0000-0003-2136-6178
Guy GorochovSorbonne Université, Inserm, Centre D'Immunologie et des Maladies Infectieuses , Paris, France.ORCID 0000-0003-2097-9677
Marion MalphettesNational Reference Center for Adult Primary Immunodefiencies, CEREDIH, Hôpital Saint-Louis, Université Paris-Cité , Paris, France.ORCID 0000-0002-9888-2528

Funding

Agence Nationale de la Recherche ANR-18-CE14-0006-01Agence Nationale de la Recherche ANR-18-IDEX-0001Agence Nationale de la Recherche ANR-21-CE17-0037Agence Nationale de la Recherche ANR-21-RHUS-0008Agence Nationale de la Recherche ANR-23-CE17-0020Agence Nationale de la Recherche RHU QUID-NASHÉmergence, Ville de ParisEuropean Innovation Council 101162457European Union 847949Fondation ARCFonds de Dotation CSL Behring pour la RechercheFrench Foundation for Medical Research EQU202203014622French National Reference Center of Primary ImmunodeficienciesInstitut National de la Santé et de la Recherche MédicaleParis Region DIM ITACSorbonne Université
6 · The paper itself

Abstract

Serum soluble CD14 (sCD14) is used as a surrogate marker for bacterial translocation. This cohort study demonstrates that higher baseline sCD14 levels are an independent biomarker for porto-sinusoidal vascular disease risk in patients with common variable immunodeficiency.

Identifiers

PMID42886038

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.