Evidence map›Paper›PMID 42884993›Full record

ReviewPolymers2026

Polymers for Detecting or Protecting Against Chemical Warfare Agents: Recent Advances and Future Perspectives.

Xiaotong Yue, Tingting Wang, Aishuo Yu, Xiaopeng Li, Min Zhang, Xiaohui Zheng, Xinglan Wang, Yingru Li, Xiaoshan Yan, Li Li and 1 more

Abstract readReview
In one paragraph

Review in Polymers, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Xiaotong YueState Key Laboratory of Chemistry for NBC Hazards Protection, Beijing 102205, China.
Tingting WangState Key Laboratory of Chemistry for NBC Hazards Protection, Beijing 102205, China.
Aishuo YuState Key Laboratory of Chemistry for NBC Hazards Protection, Beijing 102205, China.
Xiaopeng LiState Key Laboratory of Chemistry for NBC Hazards Protection, Beijing 102205, China.
Min ZhangState Key Laboratory of Chemistry for NBC Hazards Protection, Beijing 102205, China.
Xiaohui ZhengState Key Laboratory of Chemistry for NBC Hazards Protection, Beijing 102205, China.
Xinglan WangState Key Laboratory of Chemistry for NBC Hazards Protection, Beijing 102205, China.
Yingru LiKey Laboratory of Green Manufacturing of Super-Light Elastomer Materials of State Ethnic Affairs Commission, Hubei Minzu University, Enshi 445000, China.ORCID 0000-0002-3258-9230
Xiaoshan YanState Key Laboratory of Chemistry for NBC Hazards Protection, Beijing 102205, China.
Li LiState Key Laboratory of Chemistry for NBC Hazards Protection, Beijing 102205, China.
Wei HeSchool of Materials Science and Engineering, University of Science and Technology Beijing, Beijing 100083, China.

Funding

National Key Research and Development Program of China 2024YFC3015004the Joint Fund of Hubei Natural Science Foundation 2025AFD166
6 · The paper itself

Abstract

The persistent threat of chemical warfare agents (CWAs) drives the need for advanced detection and protective technologies. Polymers, with their tunable structures, ease of functionalization, and lightweight nature, have emerged as a versatile platform in this field. This review systematically summarizes recent progress in polymer-based materials for CWA sensing and protection, with emphasis on interaction mechanisms and structure-property relationships. In the realm of sensing, the working principles of polymer-based systems are rooted in electron transfer, hydrogen bonding, fluorescence quenching, and colorimetric response. Conductive polymers enable chemiresistive detection through charge transfer; hydrogen-bond acidic polymers provide selective recognition of organophosphorus agents; conjugated polymers exploit fluorescence quenching via the "molecular wire" effect; and polydiacetylenes offer visible color changes for naked-eye detection. Representative materials and their performance metrics are critically compared. For protection and decontamination, current polymer systems are designed around four synergistic mechanisms: barrier action, physical adsorption, filtration, and catalytic degradation. Barrier layers based on crosslinked networks or graphene/MOF composites suppress agent permeation while maintaining breathability. Porous polymers such as polymers of intrinsic microporosity (PIMs) and coordination polymers provide high-capacity adsorption through tailored surface functionality. Electrospun nanofiber membranes effectively filter aerosolized agents with low air resistance. Catalytic composites incorporating Zr-MOFs or single-atom catalysts enable hydrolysis of nerve agents and oxidation of blister agents under ambient conditions, with recent advances achieving self-buffering and solid-state operation. Despite significant advances, challenges remain in selectivity, environmental stability, and balancing protection with wearer comfort. Future directions point toward multifunctional systems that integrate detection, protection, and self-detoxification within wearable polymer platforms for next-generation chemical defense.

Indexed as

CWAsdegradationdetectionpolymersprotection

Identifiers

PMID42884993
PMCPMC13667212

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.