ArticlePolymers2026
Hybrid-Reinforced Phytocannabinoid-Functionalized PMMA Denture Base Composites: An In Vitro Study.
Article in Polymers, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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3 authors.
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Abstract
Polymethyl methacrylate (PMMA) remains the material of choice for denture base fabrication; however, its limited mechanical durability and susceptibility to microbial colonization continue to compromise long-term clinical performance. This study aimed to engineer a multifunctional PMMA denture base composite through hybrid reinforcement with hemp fiber (HF), silk fibroin (SF), and phytocannabinoid-rich fractions (Frac1-Frac4) and to comprehensively evaluate its mechanical, structural, antimicrobial, and cytocompatibility properties. Twenty experimental groups were fabricated, including conventional PMMA, PMMA/HF, PMMA/SF, and hybrid PMMA/HF/SF systems with or without 1 wt% phytocannabinoid fractions. Flexural strength, elastic modulus, Charpy impact strength, and Vickers hardness were determined according to standardized protocols. Structural characterization was performed using ATR-FTIR, X-ray diffraction (XRD), and scanning electron microscopy (SEM). Bacterial metabolic viability of
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