Evidence map›Paper›PMID 42884882›Full record

ArticlePlants (Basel, Switzerland)2026

Phytochemical Characterization and Integrated In Vitro Cellular Evaluation of Immunomodulatory, Cytotoxic, Genotoxic Activities and In Vivo Assessment of the Antioxidant and Anti-Arthritic Activities of

Hamza Kemchache, Hanane Khither, Khalil Kaouane, Soraya Madoui, Amina Safsaf, Khalida Hammoudi, Stefania Ponticelli, Martina Dentato, Alessia Postiglione, Daniela Rigano and 3 more

Abstract read
In one paragraph

Article in Plants (Basel, Switzerland), 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors.

Hamza KemchacheLaboratory of Applied Biochemistry, Faculty of Nature and Life Sciences, Ferhat Abbas University Setif -1-, Setif 19000, Algeria.ORCID 0009-0001-4825-2528
Hanane KhitherLaboratory of Applied Biochemistry, Faculty of Nature and Life Sciences, Ferhat Abbas University Setif -1-, Setif 19000, Algeria.ORCID 0000-0002-1601-3661
Khalil KaouaneLaboratory of Applied Biochemistry, Faculty of Nature and Life Sciences, Ferhat Abbas University Setif -1-, Setif 19000, Algeria.ORCID 0009-0009-2905-1171
Soraya MadouiLaboratory of Applied Biochemistry, Faculty of Nature and Life Sciences, Ferhat Abbas University Setif -1-, Setif 19000, Algeria.
Amina SafsafPathology Laboratory, Setif University Hospital, Setif 19000, Algeria.
Khalida HammoudiFaculty of Medecine, Ferhat Abbas University Setif -1-, Setif 19000, Algeria.
Stefania PonticelliDepartment of Biology, University of Naples Federico II, Via Cinthia 4, 80126 Napoli, Italy.
Martina DentatoDepartment of Biology, University of Naples Federico II, Via Cinthia 4, 80126 Napoli, Italy.ORCID 0009-0000-5834-9123
Alessia PostiglioneDepartment of Biology, University of Naples Federico II, Via Cinthia 4, 80126 Napoli, Italy.ORCID 0000-0002-5641-3977
Daniela RiganoDepartment of Pharmacy, School of Medicine and Surgery, University of Naples Federico II, Via Domenico Montesano 49, 80131 Naples, Italy.ORCID 0000-0002-9176-8044
Carmina SirignanoDepartment of Pharmacy, School of Medicine and Surgery, University of Naples Federico II, Via Domenico Montesano 49, 80131 Naples, Italy.
Viviana MarescaDepartment of Life Sciences, Health and Health Professions, University of Rome "Link Campus", 00165 Rome, Italy.ORCID 0000-0002-4656-320X
Chawki BensouiciNational Center for Biotechnology Research, Ali Mendjli, Nouvelle Ville UV 03, Constantine 25011, Algeria.ORCID 0000-0003-4612-4642

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Rheumatoid arthritis (RA) is a chronic autoimmune disease characterized by persistent synovial inflammation, oxidative stress, and progressive joint destruction. Given the limitations and adverse effects of current therapies, medicinal plants represent a valuable source of novel anti-inflammatory agents. This study evaluated the phytochemical composition, antioxidant, immunomodulatory, and anti-arthritic activities of an ethanolic extract of

Indexed as

anti-arthritic activityantioxidant activityoxidative stressrheumatoid arthritisUrtica urens L.

Identifiers

PMID42884882
PMCPMC13666801

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.