Evidence map›Paper›PMID 42884752›Full record

ArticleNutrients2026

Prospective Evaluation of Individualized Nutrition Support on the Incidence of High-Output Ileostomy.

Rahel M Strobel, Stella Toepfer, Konrad Neumann, Kati Engel, Michael Schumann, Wael Rayya, Christian H W Schineis, Katharina Beyer, Arved Weimann, Johannes C Lauscher

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In one paragraph

Article in Nutrients, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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1 · What the graph read from it

What it found

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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

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3 · Its place in the literature

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4 · The record

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5 · Who and what money

Authors and funding

10 authors.

Rahel M StrobelDepartment of General and Visceral Surgery, Charité-Universitätsmedizin Berlin, corporate member of Freie Universität Berlin und Humboldt-Universität zu Berlin, Campus Benjamin Franklin, Hindenburgdamm 30, 12203 Berlin, Germany.ORCID 0000-0003-1637-5467
Stella ToepferDepartment for Urology, Franziskus Krankenhaus, 10787 Berlin, Germany.
Konrad NeumannInstitute of Biometry and Clinical Epidemiology, Charité-Universitätsmedizin Berlin, corporate member of Freie Universität Berlin und Humboldt-Universität zu Berlin, 10117 Berlin, Germany.ORCID 0000-0001-9482-0971
Kati EngelDepartment of Gastroenterology, Infectiology and Rheumatology, Charité-Universitätsmedizin Berlin, corporate member of Freie Universität Berlin und Humboldt-Universität zu Berlin, 12203 Berlin, Germany.
Michael SchumannDepartment of Gastroenterology, Infectiology and Rheumatology, Charité-Universitätsmedizin Berlin, corporate member of Freie Universität Berlin und Humboldt-Universität zu Berlin, 12203 Berlin, Germany.ORCID 0000-0001-6391-9979
Wael RayyaDepartment of General and Visceral Surgery, Charité-Universitätsmedizin Berlin, corporate member of Freie Universität Berlin und Humboldt-Universität zu Berlin, Campus Benjamin Franklin, Hindenburgdamm 30, 12203 Berlin, Germany.
Christian H W SchineisDepartment of General and Visceral Surgery, Charité-Universitätsmedizin Berlin, corporate member of Freie Universität Berlin und Humboldt-Universität zu Berlin, Campus Benjamin Franklin, Hindenburgdamm 30, 12203 Berlin, Germany.ORCID 0000-0001-9189-6751
Katharina BeyerDepartment for General, Visceral and Transplantation Surgery, University Medicine Augsburg, 86156 Augsburg, Germany.
Arved WeimannDepartment of General, Visceral, and Oncological Surgery, St. George Hospital, 04129 Leipzig, Germany.ORCID 0000-0001-5474-2171
Johannes C LauscherDepartment for General, Visceral and Transplantation Surgery, University Medicine Augsburg, 86156 Augsburg, Germany.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundPatients with an ileostomy are at risk of developing a high-output ileostomy (HOS). An episode of HOS can lead to dehydration and acute kidney injury (AKI). Existing dietary recommendations are largely based on expert opinion. At Charité-Campus Benjamin Franklin, a new interdisciplinary nutrition concept was developed for patients following ileostomy creation.

methodsThis prospective, single-centre interventional study included adult patients undergoing elective surgery with the creation of an ileostomy between July 2022 and November 2024. The primary outcome was the incidence of post-discharge HOS occurring during the follow-up period. Patients received standardized postoperative meals and individualized dietary counselling. Outcomes were compared to a historical cohort.

resultsAmong 103 patients (44.2% female; median age 47.5 years), HOS occurred in 13 patients (12.6%; 95% CI 6.8-20.4%) during follow-up and in 41 of 296 patients in the historical cohort (13.9%; 95% CI, 10.4-18.3%). Patients (

conclusionsHOS incidence was not different from that observed in the historical cohort; however, the study was not designed to establish equivalence or non-inferiority. The structured nutrition pathway was feasible to implement. Post-discharge HOS was associated with readmission, acute kidney injury, and weight loss.

Indexed as

IleostomyNutritional SupportPostoperative ComplicationsAcute Kidney InjuryAdultAgedDehydrationFemaleHumansIncidenceMaleMiddle AgedPatient ReadmissionProspective Studiesclinical nutritionhigh-output stomaileostomy

Identifiers

PMID42884752
PMCPMC13666628

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