ReviewNutrients2026
Gut Microbiota and Nutritional Aspects in Pancreatic Diseases: A Narrative Review.
Review in Nutrients, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
0 citing papers in PubMed.
No citing paper in PubMed yet.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors.
Funding
Abstract
Pancreatic diseases, including acute pancreatitis (AP) and chronic pancreatitis (CP), pancreatogenic diabetes mellitus (T3cDM), autoimmune pancreatitis (AIP), and pancreatic cancer (PDAC), are associated with metabolic, inflammatory, and nutritional disturbances. Increasing evidence indicates a bidirectional relationship between pancreatic diseases and the gut microbiota. On the one hand, alterations in microbial composition and function, intestinal barrier dysfunction, and bacterial translocation may contribute to their pathogenesis and progression. On the other hand, pancreatic diseases and associated changes in nutrition and treatment may affect the composition and function of the gut microbiota. This narrative review aimed to discuss the role of the gut microbiota and nutritional aspects in selected pancreatic diseases. PubMed/MEDLINE was searched up to May 2026 for English-language publications, with emphasis on studies from the previous 10 years, while earlier relevant studies were also considered. Google Scholar was used as a supplementary source. Human observational, experimental and mechanistic studies, as well as secondary literature, were considered, addressing pancreatic microbiota, intestinal permeability, bacterial translocation, nutrition, and microbiota-targeted interventions. Available evidence indicates that pancreatic diseases are associated with alterations in gut and pancreatic microbial communities, although the reported patterns vary between diseases and studies. These changes may be relevant to intestinal barrier integrity, inflammatory signaling, microbial metabolite production, and, in pancreatic cancer, the tumor microenvironment and treatment response. Nutritional management remains an important component of care, particularly in patients with exocrine pancreatic insufficiency and those at risk of malnutrition. However, the causal relationships between pancreatic diseases and microbiota alterations remain incompletely established, and evidence for microbiota-targeted interventions is limited and heterogeneous. Further clinical studies are needed to clarify these interactions and their potential diagnostic and therapeutic relevance.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.