Trial reportNutrients2026
Exercise-Induced Dehydration Limits the Effectiveness of Post-Exercise Whey Protein Supplementation in Healthy Young Men.
Trial report in Nutrients, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
0 citing papers in PubMed.
No citing paper in PubMed yet.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
BACKGROUND/
objectivesPost-exercise protein ingestion is widely used to promote recovery from exercise, but whether exercise-induced dehydration limits the subsequent protein supplementation response remains unclear. This study examined the effects of different hydration strategies during exercise on post-exercise whey protein supplementation.
methodsThirteen healthy young men completed three partially crossover trials designed to produce approximately 2% (DEH: a dehydration trial without fluid replacement), 1% (EUH_50%: a 50% fluid-replacement trial), and 0% (EUH: a euhydration trial with 100% fluid replacement) body mass loss. Within 5 min after each exercise, participants ingested 45 g of whey protein dissolved in 450 mL of water. Serum amino acid concentrations were measured before exercise, immediately after exercise, and at 60 and 120 min after ingestion.
resultsThe protocol produced distinct exercise hydration status, with body mass loss of 2.20 ± 0.19% (DEH), 1.18 ± 0.30% (EUH_50%), and 0.27 ± 0.35% (EUH), respectively. Post-exercise whey protein ingestion increased serum amino acid concentrations in all trials. However, at 60 min after ingestion, the DEH trial showed lower total amino acid, branched-chain amino acid, leucine, isoleucine, and glutamine concentrations than both EUH_50% and EUH (all
conclusionsThese findings indicate that exercise-induced hypohydration of approximately 2.2% body mass attenuates the early circulating amino acid response to post-exercise whey protein ingestion, suggesting that inadequate fluid intake during exercise may compromise the efficacy of whey protein supplementation for post-exercise recovery.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.