ReviewNutrients2026
Nutritional Modulation of the Immuno-Biomineral Interface: From Vascular Calcification to a Hypothesis-Generating Framework for Tumor-Associated Biomineralization.
Review in Nutrients, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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4 authors.
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Abstract
Pathological biomineralization is increasingly recognized as a regulated biological process involving interactions among mineral metabolism, inflammation, cellular stress, extracellular vesicles (EVs), extracellular matrix (ECM) components, and mineral precursors. These processes are particularly well characterized in vascular calcification, where immune, metabolic, vesicular, and matrix-associated pathways contribute to ectopic mineral deposition. Tumor-associated mineralization is also documented in several malignancies, but its cellular origins, mineral composition, and biological significance remain substantially less defined. The Immuno-Biomineral Interface (IBI) is proposed here as a hypothesis-generating conceptual framework for integrating these interacting processes and examining potential mechanistic connections between established vascular calcification pathways and tumor-associated biomineralization. Nutritional status can modulateseveral biological processes implicated in pathological calcification, including mineral homeostasis, inflammatory signaling, oxidative stress, ECM remodeling, and EV biology. Magnesium, vitamin K
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