Evidence map›Paper›PMID 42884640›Full record

ReviewNutrients2026

Practical Approaches to Nutritional Interventions for Malnutrition, Sarcopenia, and Frailty in Community-Dwelling Older Adults and Care Home Populations: A Narrative Review.

Haya Khalaf, Camilla Hopwood, Caryn Straker, Kirsty Donald, Nuno Lopes, Adrian Slee

Abstract readReview
In one paragraph

Review in Nutrients, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Haya KhalafDivision of Medicine, Faculty of Medical Sciences, University College London (UCL), London WC1E 6BT, UK.
Camilla HopwoodAYMES International Ltd., Unit B, Sunnyhills Road, Leek ST13 5RJ, UK.
Caryn StrakerNightingale Hammerson Care Home, London SW12 8NB, UK.
Kirsty DonaldAYMES International Ltd., Unit B, Sunnyhills Road, Leek ST13 5RJ, UK.
Nuno LopesKYN Hurlingham, 28 Daisy Lane, London SW6 3DD, UK.
Adrian SleeDivision of Medicine, Faculty of Medical Sciences, University College London (UCL), London WC1E 6BT, UK.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundAverage life expectancy has increased substantially on a global scale; this demographic shift presents considerable public health challenges, as increased longevity is accompanied by higher prevalence of chronic diseases, functional decline, and dependency. Malnutrition, sarcopenia, and frailty frequently coexist in older adults, particularly among care home residents. These interrelated conditions contribute to adverse clinical outcomes including falls, hospitalisation, and reduced quality of life. Despite their growing recognition, gaps remain in understanding optimal nutritional intervention strategies and their implementation in care home settings. PURPOSE AND SCOPE: This literature review examines the interplay between malnutrition, sarcopenia, and frailty in older adults, with particular focus on care home populations. The review evaluates evidence-based nutritional interventions, including the Food First approach, food fortification, and oral nutritional supplements (ONSs), and explores factors influencing intervention adherence and effectiveness. MAIN FINDINGS AND

conclusionsEvidence demonstrates that malnutrition, sarcopenia, and frailty share common pathophysiological mechanisms and overlapping clinical features such as unintended weight loss and age-related loss of muscle mass and strength yet represent distinct conditions requiring targeted assessment and intervention. While food fortification effectively increases energy and protein intake, when insufficient, ONS have been shown to significantly increase energy intake, BMI, as well as improve functional outcomes, reduce hospitalisation rates, and demonstrate cost effectiveness. However, adherence remains challenging and can be affected by barriers related to personal, contextual or product-related factors. Such nutritional strategies, particularly when combined with others such as physical activity/exercise as part of a multimodal approach, and focusing on providing an individualised, patient-centred care may help to achieve optimal outcomes in older adults. Further research is needed to establish standardised protocols for implementing combined nutritional and multimodal strategies in diverse care environments to optimise health outcomes for older adults.

Indexed as

FrailtyMalnutritionNutrition TherapySarcopeniaAgedAged, 80 and overAging in PlaceDietary SupplementsFood, FortifiedFrail ElderlyHumansIndependent LivingNursing Home ResidentsNutritional StatusQuality of Lifecare homesFood First approachfrailtymalnutritionoral nutrition supplementationsarcopenia

Identifiers

PMID42884640
PMCPMC13666933

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.