Evidence map›Paper›PMID 42884638›Full record

ReviewNutrients2026

Nutritional Care in Cystic Fibrosis Across the Arab World: Regional Heterogeneity, Current Evidence, and Future Directions.

Ala K Shaikhkhalil, Mutasim Abu-Hasan, Serena Sharpe, Fadi Asfour

Abstract readReview
In one paragraph

Review in Nutrients, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Ala K ShaikhkhalilDivision of Pediatric Gastroenterology, Hepatology and Nutrition, Sheikh Khalifa Medical City, Abu Dhabi P.O. Box 51900, United Arab Emirates.
Mutasim Abu-HasanPulmonary Medicine, Sidra Medicine, Doha P.O. Box 26999, Qatar.ORCID 0000-0002-0470-334X
Serena SharpeClinical Nutrition and Allied Health, Sidra Medicine, Doha P.O. Box 26999, Qatar.ORCID 0009-0008-9456-2990
Fadi AsfourDepartment of Pediatrics, University of Utah, Salt Lake City, UT 84413, USA.ORCID 0000-0001-6317-6845

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundcystic fibrosis (CF) is a genetic disease which was previously thought to predominantly affect people of European ancestry but has been increasingly diagnosed in other populations. Although respiratory disease is the principal manifestation, poor nutritional status is a central determinant of pulmonary outcomes and survival. There are gaps in the literature on epidemiology, genetics, clinical manifestations and nutritional outcomes of CF in the Arab world.

methodsin this narrative review, we aim to synthesize and analyze nutrition-relevant data and explore how these relate to epidemiology, diagnostic pathways, genotype-phenotype relationships, and availability and access to care.

resultsthe published evidence across the region is heterogenous in nature but shows that malnutrition in CF is dominant in reported pediatric cohorts. The overall poor nutritional outcomes of CF in the Arab world reflect the multifactorial effects of disease biology, diagnostics, healthcare capacity, and treatment access, as well as psychosocial and social and structural determinants of health.

conclusionsimproving CF-related nutritional status in the region requires early diagnosis of the disease, ideally through newborn screening, proactive intervention, multidisciplinary care, access to therapies including modulator therapy, and the establishment of collaborative registries that capture existing genetic diversity and healthcare disparities while tracking clinical and nutritional outcomes.

Indexed as

ArabsCystic FibrosisMalnutritionNutritional StatusChildHealthcare DisparitiesHumansInfant, NewbornMiddle EastArab worldCFTR modulatorscystic fibrosisgrowthhealth disparitiesmalnutritionMiddle East and North Africanutritionpancreatic enzyme replacement therapypancreatic insufficiency

Identifiers

PMID42884638
PMCPMC13667151

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.