Evidence map›Paper›PMID 42884168›Full record

ArticleInternational journal of molecular sciences2026

Integrated Transcriptomic and Network Analysis Identifies Candidate Kinase-Mediated Thyroid-Associated Targets of Withaferin A.

Ejlal Mohamed Abdullah, Alaa Alnoor Alameen, Nouf Omar AlAfaleq, Mona Shujaa Alharbi

Abstract read
In one paragraph

Article in International journal of molecular sciences, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Ejlal Mohamed AbdullahDepartment of Biochemistry, College of Science, King Saud University, P.O. Box 2455, Riyadh 11451, Saudi Arabia.
Alaa Alnoor AlameenDepartment of Pharmacology and Toxicology, College of Pharmacy, King Saud University, P.O. Box 2457, Riyadh 11451, Saudi Arabia.
Nouf Omar AlAfaleqDepartment of Biochemistry, College of Science, King Saud University, P.O. Box 2455, Riyadh 11451, Saudi Arabia.ORCID 0000-0003-1868-4706
Mona Shujaa AlharbiDepartment of Biochemistry, College of Science, King Saud University, P.O. Box 2455, Riyadh 11451, Saudi Arabia.ORCID 0009-0007-4274-244X

Funding

Ongoing Research Funding Program ORF-2026-1950
6 · The paper itself

Abstract

Withaferin A (WA), a bioactive steroidal lactone derived from

Indexed as

Gene Regulatory NetworksThyroid GlandTranscriptomeWithanolidesGene Expression ProfilingHumansHypothyroidismMolecular Docking SimulationMolecular Dynamics SimulationProtein Interaction Mapswithaferin AWithanolideshypothyroidismkinase enrichmentmolecular dockingmolecular dynamicstranscriptomicswithaferin A

Identifiers

PMID42884168
PMCPMC13665287

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.