Parameter-Based Prioritization of Time-Resolved LC-HRMS Ion Tracks for Untargeted Reaction Monitoring.

Igor Ilyasov, Arcady Braun, Vera Olicheva, Valery Goman, Victoria Grikh, Anastasiya Zhevlakova, Irina Selivanova, Vladimir Beloborodov

Abstract read

PubMed Full text at PMC Publisher

In one paragraph

Article in International journal of molecular sciences, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it

0cells of the map it votes in

0citing papers in PubMed

–field-weighted citation impact

1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Igor IlyasovDepartment of Chemistry, Nelyubin Institute of Pharmacy, Sechenov First Moscow State Medical University, Trubetskaya Street 8/2, 119048 Moscow, Russia.

Arcady BraunDepartment of Chemistry, Lomonosov Moscow State University, 27/1 Lomonosovsky Avenue, 119991 Moscow, Russia.ORCID 0000-0003-2955-996X

Vera OlichevaDepartment of Chemistry, Nelyubin Institute of Pharmacy, Sechenov First Moscow State Medical University, Trubetskaya Street 8/2, 119048 Moscow, Russia.ORCID 0009-0004-6866-218X

Valery GomanDepartment of Chemistry, Nelyubin Institute of Pharmacy, Sechenov First Moscow State Medical University, Trubetskaya Street 8/2, 119048 Moscow, Russia.ORCID 0009-0006-2250-3671

Victoria GrikhDepartment of Analytical, Physical and Colloidal Chemistry, Nelyubin Institute of Pharmacy, Sechenov First Moscow State Medical University, Trubetskaya Street 8/2, 119048 Moscow, Russia.

Anastasiya ZhevlakovaDepartment of Chemistry, Nelyubin Institute of Pharmacy, Sechenov First Moscow State Medical University, Trubetskaya Street 8/2, 119048 Moscow, Russia.ORCID 0000-0002-2945-9806

Irina SelivanovaDepartment of Chemistry, Nelyubin Institute of Pharmacy, Sechenov First Moscow State Medical University, Trubetskaya Street 8/2, 119048 Moscow, Russia.ORCID 0000-0002-2244-445X

Vladimir BeloborodovDepartment of Chemistry, Nelyubin Institute of Pharmacy, Sechenov First Moscow State Medical University, Trubetskaya Street 8/2, 119048 Moscow, Russia.

Funding

Russian Science Foundation 25-25-00537

6 · The paper itself

Abstract

Herein, an automated, parameter-based workflow is introduced for processing time-resolved high-resolution mass spectrometry (HRMS) data. Its utility is demonstrated using the reaction between the ABTS

Indexed as

Liquid Chromatography-Mass SpectrometryMass SpectrometryAlgorithmsAntioxidantsBenzothiazolesChromatography, High Pressure LiquidFlavanonesIonsKineticsSoftwareSulfonic Acids2,2'-azino-di-(3-ethylbenzothiazoline)-6-sulfonic acidAntioxidantsBenzothiazolesFlavanonesIonsnaringeninSulfonic Acidshigh-resolution mass spectrometryion prioritizationLC–HRMSreaction monitoringtime-resolved analysisuntargeted analysis

Identifiers

PMID42884097

DOI10.3390/ijms27198852

PMCPMC13664802

What OpenQuestion holds

Textmetadata

Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.