Evidence map›Paper›PMID 42884062›Full record

ArticleInternational journal of molecular sciences2026

Combined Effects of

Kabita Kuikel, Amy McEwen, Tahlia Joy Mathiske, Lucinda Wojtaszak, James A St John, Ali Delbaz

Abstract read
In one paragraph

Article in International journal of molecular sciences, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Kabita KuikelClem Jones Centre for Neurobiology and Stem Cell Research, Institute for Biomedicine and Glycomics, Griffith University, Gold Coast, QLD 4215, Australia.
Amy McEwenClem Jones Centre for Neurobiology and Stem Cell Research, Institute for Biomedicine and Glycomics, Griffith University, Gold Coast, QLD 4215, Australia.ORCID 0000-0002-0147-7973
Tahlia Joy MathiskeClem Jones Centre for Neurobiology and Stem Cell Research, Institute for Biomedicine and Glycomics, Griffith University, Gold Coast, QLD 4215, Australia.
Lucinda WojtaszakClem Jones Centre for Neurobiology and Stem Cell Research, Institute for Biomedicine and Glycomics, Griffith University, Gold Coast, QLD 4215, Australia.
James A St JohnClem Jones Centre for Neurobiology and Stem Cell Research, Institute for Biomedicine and Glycomics, Griffith University, Gold Coast, QLD 4215, Australia.ORCID 0000-0001-7536-3381
Ali DelbazClem Jones Centre for Neurobiology and Stem Cell Research, Institute for Biomedicine and Glycomics, Griffith University, Gold Coast, QLD 4215, Australia.ORCID 0009-0006-0500-3595

Funding

Clem Jones FoundationGoda Foundation
6 · The paper itself

Abstract

Alzheimer's disease involves complex interactions among neuroinflammation and metabolic dysfunction. Emerging evidence implicates microbial pathogens and hypoxia as converging stressors, yet their combined impact on glial function remains poorly understood. Human astrocyte and microglial cell lines were exposed to four experimental conditions: (i) normoxic control, (ii)

Indexed as

Alzheimer DiseaseChlamydia InfectionsChlamydophila InfectionsChlamydophila pneumoniaeHypoxiaNeurogliaAmyloid beta-PeptidesAstrocytesCell HypoxiaCell LineHumansMicrogliaProteomicsAmyloid beta-PeptidesAlzheimer’s diseaseamyloid-βChlamydia pneumoniaedual stress responseglial immunometabolismglial metabolismhypoxia

Identifiers

PMID42884062
PMCPMC13665377

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.