Evidence map›Paper›PMID 42884038›Full record

ArticleInternational journal of molecular sciences2026

Translational Toxicology of

Marta Bassi, Sabrine Bilel, Giorgia Corli, Nicole Cocita, Asia Masoli, Tatiana Bernardi, Sara Odoardi, Serena Mestria, Giulia Biosa, Sabina Strano-Rossi and 1 more

Abstract read
In one paragraph

Article in International journal of molecular sciences, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Marta BassiDepartment of Translational Medicine, Section of Legal Medicine, LTTA Center and University Center of Gender Medicine, University of Ferrara, 44121 Ferrara, Italy.ORCID 0009-0008-3753-4627
Sabrine BilelDepartment of Environmental Sciences and Prevention, University of Ferrara, 44121 Ferrara, Italy.ORCID 0000-0003-1515-980X
Giorgia CorliDepartment of Translational Medicine, Section of Legal Medicine, LTTA Center and University Center of Gender Medicine, University of Ferrara, 44121 Ferrara, Italy.ORCID 0000-0002-2973-2446
Nicole CocitaDepartment of Translational Medicine, Section of Legal Medicine, LTTA Center and University Center of Gender Medicine, University of Ferrara, 44121 Ferrara, Italy.ORCID 0009-0008-3796-1274
Asia MasoliDepartment of Translational Medicine, Section of Legal Medicine, LTTA Center and University Center of Gender Medicine, University of Ferrara, 44121 Ferrara, Italy.ORCID 0009-0002-6342-3732
Tatiana BernardiDepartment of Chemical, Pharmaceutical and Agricultural Sciences, University of Ferrara, 44121 Ferrara, Italy.
Sara OdoardiForensic Toxicology Laboratory, Department of Healthcare Surveillance and Bioethics, Università Cattolica del Sacro Cuore F. Policlinico Gemelli IRCCS, 00168 Rome, Italy.ORCID 0000-0002-5143-8649
Serena MestriaForensic Toxicology Laboratory, Department of Healthcare Surveillance and Bioethics, Università Cattolica del Sacro Cuore F. Policlinico Gemelli IRCCS, 00168 Rome, Italy.ORCID 0000-0003-4261-8231
Giulia BiosaForensic Toxicology Laboratory, Department of Healthcare Surveillance and Bioethics, Università Cattolica del Sacro Cuore F. Policlinico Gemelli IRCCS, 00168 Rome, Italy.
Sabina Strano-RossiForensic Toxicology Laboratory, Department of Healthcare Surveillance and Bioethics, Università Cattolica del Sacro Cuore F. Policlinico Gemelli IRCCS, 00168 Rome, Italy.ORCID 0000-0001-7530-2968
Matteo MartiDepartment of Translational Medicine, Section of Legal Medicine, LTTA Center and University Center of Gender Medicine, University of Ferrara, 44121 Ferrara, Italy.ORCID 0000-0001-8751-2882

Funding

Department of Anti-Drug Policies and Other Addictions, Presidency of the Council of Ministers project: "Effects of NPS: development of a multicentric research for the information enhancement of the Early Warning System" to MMDepartment of Anti-Drug Policies and Other Addictions, Presidency of the Council of Ministers project: "Implementation of the identification and study of the effects of NPS: Development of a multicentric research to strengthen the database of the National Monitoring Centre for Drug Addiction and the Early Warning System" to MMDepartment of Anti-Drug Policies and Other Addictions, Presidency of the Council of Ministers project "Multicentric research for the study of the pharmaco-toxicological and the analytical identification of Novel Synthetic Opioids and NPS" to MMUniversity of Ferrara FAR 2023 to MMUniversity of Ferrara FAR 2024 to MM
6 · The paper itself

Abstract

The novel psychoactive substance (NPS) phenomenon represents a major global problem. Despite the methodical inclusion of new analogues in lists of controlled drugs, new compounds continue to circulate, frequently resulting in fatal intoxications. The emergence of N-isopropyl butylone (NiPB) in 2024, found as an adulterant in methamphetamine-based products, underscores the rapidly evolving landscape of NPSs. Despite its structural similarity to potent monoamine transporter inhibitors, specific pharmacological data and information on its effects in consumers are currently lacking. This study aims to characterize the acute physiological, behavioural, and sensorimotor effects of NiPB (0.1-60 mg/kg; i.p.) in male mice, complemented by in silico pharmacokinetic modelling (ADMET Predictor

Indexed as

AlkaloidsButanesPsychotropic DrugsAnimalsComputer SimulationMaleMiceSynthetic CathinoneAlkaloidsButanescathinonePsychotropic DrugsSynthetic CathinoneADMETbehavioural and physiological effectsNiPBN-isopropyl butyloneNPS

Identifiers

PMID42884038
PMCPMC13665128

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.