Evidence map›Paper›PMID 42884026›Full record

ArticleInternational journal of molecular sciences2026

Fructus Sophorae Extract Generated Using the Natural Deep Eutectic Solvent ChCl Urea Activates Wnt/β Catenin and cAMP/MITF Signaling to Stimulate Hair Growth and Pigmentation.

Gary Ka-Wing Yuen, Yinzhi Li, Tina Ting-Xia Dong, Karl Wah-Keung Tsim

Abstract read
In one paragraph

Article in International journal of molecular sciences, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Gary Ka-Wing YuenDivision of Life Science, Centre for Chinese Medicine, and State Key Laboratory of Molecular Neuroscience, The Hong Kong University of Science and Technology, Hong Kong, China.
Yinzhi LiDivision of Life Science, Centre for Chinese Medicine, and State Key Laboratory of Molecular Neuroscience, The Hong Kong University of Science and Technology, Hong Kong, China.
Tina Ting-Xia DongDivision of Life Science, Centre for Chinese Medicine, and State Key Laboratory of Molecular Neuroscience, The Hong Kong University of Science and Technology, Hong Kong, China.
Karl Wah-Keung TsimDivision of Life Science, Centre for Chinese Medicine, and State Key Laboratory of Molecular Neuroscience, The Hong Kong University of Science and Technology, Hong Kong, China.ORCID 0000-0003-4808-1674

Funding

Chinese Medicine Development Fund 24B1-2/053A_R1Innovation and Technology Commission PRP/096/24FX, ITCPD/17-9, ITC-CNERC14SC01, Laboratory for Synthetic Chemistry and Chemical Biology' under the Health@InnoHK Program and State Key Laboratory of Synthetic ChemistryShenzhen Science and Technology Innovation Commission ZDSYS201707281432317
6 · The paper itself

Abstract

Androgenetic alopecia remains challenging to treat, with limited FDA-approved therapies. Natural products, such as the fruit of

Indexed as

HairPigmentationPlant ExtractsSophoraSophora japonicaWnt Signaling PathwayAnimalsbeta CateninCyclic AMPFruitHair FollicleMiceSignal TransductionSolventsbeta CateninCyclic AMPPlant ExtractsSolventsalopeciahair growthnatural deep eutectic solventsSophora japonicasophoricoside

Identifiers

PMID42884026
PMCPMC13664810

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.