Evidence map›Paper›PMID 42884001›Full record

ArticleInternational journal of molecular sciences2026

Curcumin-Based Tyrosinase-Targeting Derivatives for Cell Imaging and Depigmenting Effect.

Maura Monforte, Marilena Pontoriero, Paola Maria Bonaccorsi, Antonella Calderaro, Leonardo Centorrino, Valeria D'Angelo, Laura De Luca, Maria Paola Germanò, Rosaria Gitto, Salvatore Mirabile and 4 more

Abstract read
In one paragraph

Article in International journal of molecular sciences, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors.

Maura MonforteDepartment of Chemical, Biological, Pharmaceutical, and Environmental Sciences, University of Messina, Viale F. Stagno d'Alcontres 31, 98166 Messina, Italy.
Marilena PontorieroProteomics and Tumor Biochemistry Group, Department of Experimental and Clinical Medicine, School of Medicine, Magna Græcia University of Catanzaro, Viale Europa, 88100 Catanzaro, Italy.ORCID 0009-0004-0941-9075
Paola Maria BonaccorsiDepartment of Chemical, Biological, Pharmaceutical, and Environmental Sciences, University of Messina, Viale F. Stagno d'Alcontres 31, 98166 Messina, Italy.ORCID 0000-0002-7914-5653
Antonella CalderaroDepartment of Chemical, Biological, Pharmaceutical, and Environmental Sciences, University of Messina, Viale F. Stagno d'Alcontres 31, 98166 Messina, Italy.
Leonardo CentorrinoDepartment of Chemical, Biological, Pharmaceutical, and Environmental Sciences, University of Messina, Viale F. Stagno d'Alcontres 31, 98166 Messina, Italy.ORCID 0009-0006-1438-0333
Valeria D'AngeloDepartment of Chemical, Biological, Pharmaceutical, and Environmental Sciences, University of Messina, Viale F. Stagno d'Alcontres 31, 98166 Messina, Italy.
Laura De LucaDepartment of Chemical, Biological, Pharmaceutical, and Environmental Sciences, University of Messina, Viale F. Stagno d'Alcontres 31, 98166 Messina, Italy.ORCID 0000-0003-0614-5713
Maria Paola GermanòDepartment of Chemical, Biological, Pharmaceutical, and Environmental Sciences, University of Messina, Viale F. Stagno d'Alcontres 31, 98166 Messina, Italy.
Rosaria GittoDepartment of Chemical, Biological, Pharmaceutical, and Environmental Sciences, University of Messina, Viale F. Stagno d'Alcontres 31, 98166 Messina, Italy.ORCID 0000-0003-0002-2253
Salvatore MirabileDepartment of Chemical, Biological, Pharmaceutical, and Environmental Sciences, University of Messina, Viale F. Stagno d'Alcontres 31, 98166 Messina, Italy.ORCID 0009-0004-1882-5016
Giuseppe Tancredi PatanèDepartment of Chemical, Biological, Pharmaceutical, and Environmental Sciences, University of Messina, Viale F. Stagno d'Alcontres 31, 98166 Messina, Italy.ORCID 0009-0005-0792-5895
Stefano PutaggioDepartment of Chemical, Biological, Pharmaceutical, and Environmental Sciences, University of Messina, Viale F. Stagno d'Alcontres 31, 98166 Messina, Italy.
Domenica ScumaciProteomics and Tumor Biochemistry Group, Department of Experimental and Clinical Medicine, School of Medicine, Magna Græcia University of Catanzaro, Viale Europa, 88100 Catanzaro, Italy.ORCID 0000-0002-8117-834X
Chiara Maria Antonietta GangemiDepartment of Chemical, Biological, Pharmaceutical, and Environmental Sciences, University of Messina, Viale F. Stagno d'Alcontres 31, 98166 Messina, Italy.ORCID 0000-0002-6978-1779

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Targeting melanogenesis through tyrosinase inhibition represents a key therapeutic strategy, highlighting the need for novel molecules capable of modulating melanin synthesis and/or serving as fluorescent probes for cellular and melanoma tracking. In this study, two curcumin (CUR) derivatives,

Indexed as

CurcuminEnzyme InhibitorsMonophenol MonooxygenaseSkin Lightening PreparationsAgaricusAnimalsCell Line, TumorFluorescent Chemosensor CompoundsHumansMelaninsMelanogenesisMelanoma, ExperimentalMiceMolecular Docking SimulationZebrafishCurcuminEnzyme InhibitorsFluorescent Chemosensor CompoundsMelaninsMonophenol MonooxygenaseSkin Lightening Preparationsantioxidantcurcumin derivativesdepigmentingfluorescence imagingtyrosinase

Identifiers

PMID42884001
PMCPMC13665293

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.