ArticleInternational journal of molecular sciences2026
Intercellular Transfer of CD155 Mediated by Melanoma Extracellular Vesicles Downregulates DNAM-1 Expression on NK Cells.
Li-Ying Wu, Luize Goncalves Lima, Sunyoung Ham, Mina Lim, Su-Ho Park, Yue Su, Xuanxuan Li, Edna Pei Zhi Chai, Matthias Braun, Yong-Soo Choi and 2 more
Abstract read
In one paragraphArticle in International journal of molecular sciences, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
2 · The registryThe trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
3 · Its place in the literatureWho cites it
0 citing papers in PubMed.
No citing paper in PubMed yet.
4 · The recordCorrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
5 · Who and what moneyAuthors and funding
12 authors.
Li-Ying WuTumour Microenvironment Laboratory, QIMR Berghofer Medical Research Institute, Herston, QLD 4006, Australia.ORCID 0000-0002-1509-9440 Luize Goncalves LimaTumour Microenvironment Laboratory, QIMR Berghofer Medical Research Institute, Herston, QLD 4006, Australia.
Sunyoung HamJC STEM Lab of Personalised Cancer Medicine, Li Ka Shing Institute of Health Sciences, The Chinese University of Hong Kong, Hong Kong SAR, China.
Mina LimDepartment of Bioconvergence Science, Graduate School, CHA University, Seongnam 13488, Republic of Korea.
Su-Ho ParkJC STEM Lab of Personalised Cancer Medicine, Li Ka Shing Institute of Health Sciences, The Chinese University of Hong Kong, Hong Kong SAR, China.
Yue SuJC STEM Lab of Personalised Cancer Medicine, Li Ka Shing Institute of Health Sciences, The Chinese University of Hong Kong, Hong Kong SAR, China.ORCID 0009-0003-6398-1571 Xuanxuan LiJC STEM Lab of Personalised Cancer Medicine, Li Ka Shing Institute of Health Sciences, The Chinese University of Hong Kong, Hong Kong SAR, China.
Edna Pei Zhi ChaiTumour Microenvironment Laboratory, QIMR Berghofer Medical Research Institute, Herston, QLD 4006, Australia.
Matthias BraunDepartment of Paediatric Haematology, Oncology and Immunodeficiency, Justus-Liebig-University Giessen, 35392 Giessen, Germany.ORCID 0009-0003-9211-5090 Yong-Soo ChoiDepartment of Medicinal Biosciences and Bioengineering, Bioengineering, Inha University, Incheon 22212, Republic of Korea.ORCID 0000-0001-8445-8067 Tobias BaldInstitute for Experimental Oncology, University Hospital Bonn, 53127 Bonn, Germany.
Andreas MöllerTumour Microenvironment Laboratory, QIMR Berghofer Medical Research Institute, Herston, QLD 4006, Australia.ORCID 0000-0002-8618-6998 Funding
Cancer Council Queensland ACCR027Chinese University of Hong Kong IDBF23MED14Deutsche Forschungsgemeinschaft EXC2151-390873048Hong Kong Jockey Club Charities Trust 2023-0031Innovation and Technology Commission GSP153Innovation and Technology Commission PiH/048-050/22GSMelanoma Research Alliance 693786
6 · The paper itselfAbstract
Melanoma is a highly immunogenic cancer, and immunotherapy is the first-line treatment for patients with advanced disease. However, CD155 overexpression in melanoma has been associated with resistance to immunotherapy. Whether CD155 can be transferred from tumour cells via extracellular vesicles (EVs), and how this transfer affects immune responses in melanoma, remains unclear. To investigate melanoma cell transfer of CD155 in vivo, B16F10-WT and B16F10-CD155KO melanoma cells were subcutaneously injected into CD155
Indexed as
Antigens, Differentiation, T-LymphocyteExtracellular VesiclesKiller Cells, NaturalMelanomaMelanoma, ExperimentalReceptors, VirusAnimalsCell Line, TumorDown-RegulationGene Expression Regulation, NeoplasticHumansMiceMice, Inbred C57BLMice, KnockoutT Lineage-Specific Activation Antigen 1Antigens, Differentiation, T-Lymphocytepoliovirus receptorReceptors, VirusT Lineage-Specific Activation Antigen 1CD155DNAM-1 (CD226)extracellular vesiclesmelanomanatural killer (NK) cellstumour microenvironment
Identifiers
PMID42883943
PMCPMC13664779
What OpenQuestion holds
Textmetadata
Read underepoch 390