Observational studyInternational journal of molecular sciences2026
Prognostic Value and Longitudinal Dynamics of Multigene Circulating Tumor DNA in Advanced Pancreatic Cancer Treated with 5-Fluorouracil-Based Chemotherapy.
Gi Yeon Lee, Jung Won Chun, Dong-Eun Lee, Jun-Ha Jang, Woo Jin Lee, Hwang-Phill Kim, Seung-Tae Lee, Sang Myung Woo, Sun-Young Kong
Abstract readObservational Study
In one paragraphObservational study in International journal of molecular sciences, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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0citing papers in PubMed
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What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
2 · The registryThe trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
3 · Its place in the literatureWho cites it
0 citing papers in PubMed.
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4 · The recordCorrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
5 · Who and what moneyAuthors and funding
9 authors.
Gi Yeon LeeTargeted Therapy Branch, National Cancer Center, 323 Ilsan-ro, Ilsandong-gu, Goyang-si 10408, Republic of Korea.
Jung Won ChunCenter for Liver and Pancreatobiliary Cancer, National Cancer Center, 323 Ilsan-ro, Ilsandong-gu, Goyang-si 10408, Republic of Korea.ORCID 0000-0003-1964-7501 Dong-Eun LeeBiostatistics Collaboration Team, National Cancer Center, 323 Ilsan-ro, Ilsandong-gu, Goyang-si 10408, Republic of Korea.
Jun-Ha JangTargeted Therapy Branch, National Cancer Center, 323 Ilsan-ro, Ilsandong-gu, Goyang-si 10408, Republic of Korea.ORCID 0009-0002-4972-2306 Woo Jin LeeCenter for Liver and Pancreatobiliary Cancer, National Cancer Center, 323 Ilsan-ro, Ilsandong-gu, Goyang-si 10408, Republic of Korea.ORCID 0000-0003-2115-6701 Hwang-Phill KimIMBdx, 38 Teheran-ro 113-gil, Gangnam-gu, Seoul 06173, Republic of Korea.
Seung-Tae LeeDepartment of Laboratory Medicine, Yonsei University College of Medicine, 50-1 Yonsei-ro, Seodaemun-gu, Seoul 03722, Republic of Korea.ORCID 0000-0003-1047-1415 Sang Myung WooCenter for Liver and Pancreatobiliary Cancer, National Cancer Center, 323 Ilsan-ro, Ilsandong-gu, Goyang-si 10408, Republic of Korea.ORCID 0000-0003-3786-4403 Sun-Young KongTargeted Therapy Branch, National Cancer Center, 323 Ilsan-ro, Ilsandong-gu, Goyang-si 10408, Republic of Korea.ORCID 0000-0003-0620-4058 Funding
imbdxNational Research Foundation of Korea RS-2025-19542979
6 · The paper itselfAbstract
Circulating tumor DNA (ctDNA) is a minimally invasive biomarker in pancreatic ductal adenocarcinoma (PDAC), but the prognostic information added by multigene ctDNA metrics beyond
Indexed as
Carcinoma, Pancreatic DuctalCirculating Tumor DNAFluorouracilPancreatic NeoplasmsAgedBiomarkers, TumorCA-19-9 AntigenFemaleHumansMaleMiddle AgedPilot ProjectsPrognosisProspective StudiesProto-Oncogene Proteins p21(ras)Biomarkers, TumorCA-19-9 AntigenCirculating Tumor DNAFluorouracilKRAS protein, humanProto-Oncogene Proteins p21(ras)5-fluorouracilCA19-9circulating tumor DNAliquid biopsylongitudinal monitoringpancreatic ductal adenocarcinomaprognosisvariant allele frequency
Identifiers
PMID42883913
PMCPMC13664952
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