Evidence map›Paper›PMID 42883841›Full record

ArticleInternational journal of molecular sciences2026

Comprehensive circRNA Profiling Reveals a Testis-Specific circRNA circdmrt1 as a Novel Regulator of Gonadal Development in Crucian Carp.

Dongmei Zhong, Faxiang Li, Ziyu Yang, Fang Gou, Yanmei Gao, Tian Bu, Qingfeng Liu, Yinggang Li, Wuhui Li, Qizhi Liu and 3 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in International journal of molecular sciences, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors.

Dongmei ZhongEngineering Research Center of Polyploid Fish Reproduction and Breeding of the State Education Ministry, College of Life Sciences, Hunan Normal University, Changsha 410081, China.
Faxiang LiMOE Key Laboratory of Rare Pediatric Diseases, Center for Medical Genetics, School of Life Sciences, Central South University, Changsha 410081, China.
Ziyu YangEngineering Research Center of Polyploid Fish Reproduction and Breeding of the State Education Ministry, College of Life Sciences, Hunan Normal University, Changsha 410081, China.
Fang GouEngineering Research Center of Polyploid Fish Reproduction and Breeding of the State Education Ministry, College of Life Sciences, Hunan Normal University, Changsha 410081, China.ORCID 0009-0005-4986-041X
Yanmei GaoEngineering Research Center of Polyploid Fish Reproduction and Breeding of the State Education Ministry, College of Life Sciences, Hunan Normal University, Changsha 410081, China.
Tian BuEngineering Research Center of Polyploid Fish Reproduction and Breeding of the State Education Ministry, College of Life Sciences, Hunan Normal University, Changsha 410081, China.
Qingfeng LiuEngineering Research Center of Polyploid Fish Reproduction and Breeding of the State Education Ministry, College of Life Sciences, Hunan Normal University, Changsha 410081, China.
Yinggang LiEngineering Research Center of Polyploid Fish Reproduction and Breeding of the State Education Ministry, College of Life Sciences, Hunan Normal University, Changsha 410081, China.
Wuhui LiEngineering Research Center of Polyploid Fish Reproduction and Breeding of the State Education Ministry, College of Life Sciences, Hunan Normal University, Changsha 410081, China.
Qizhi LiuEngineering Research Center of Polyploid Fish Reproduction and Breeding of the State Education Ministry, College of Life Sciences, Hunan Normal University, Changsha 410081, China.
Kaikun LuoEngineering Research Center of Polyploid Fish Reproduction and Breeding of the State Education Ministry, College of Life Sciences, Hunan Normal University, Changsha 410081, China.
Rong YangEngineering Research Center of Polyploid Fish Reproduction and Breeding of the State Education Ministry, College of Life Sciences, Hunan Normal University, Changsha 410081, China.ORCID 0009-0000-8066-2386
Shaojun LiuEngineering Research Center of Polyploid Fish Reproduction and Breeding of the State Education Ministry, College of Life Sciences, Hunan Normal University, Changsha 410081, China.

Funding

National Natural Science Foundation of China 32200129National Natural Science Foundation of China 32293252National Natural Science Foundation of China 32370742
6 · The paper itself

Abstract

Fish gonad development is a central process in reproductive regulation, and elucidating its molecular mechanisms is highly important for developing aquatic genetic resources. However, the involvement of circular RNAs (circRNAs) in the gonad development of freshwater fish is unknown. In this study, a dynamic expression profile of circRNA during the development of red crucian carp testes was systematically constructed via whole-transcriptome sequencing. Notably, the circular characteristics and high testis-specific expression of the key circRNA circdmrt1, formed through the reverse splicing of the fourth exon of the

Indexed as

CarpsGonadsRNA, CircularTestisAnimalsCell ProliferationGene Expression ProfilingGene Expression Regulation, DevelopmentalHEK293 CellsHumansMaleMicroRNAsRNA, Competitive EndogenousTranscription FactorsDMRT1 proteinMicroRNAsRNA, CircularRNA, Competitive EndogenousTranscription Factorscircular RNAsgonad developmentmiRNAwhole-transcriptome sequencing

Identifiers

PMID42883841
PMCPMC13664762

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.