Evidence map›Paper›PMID 42883779›Full record

ArticleInternational journal of molecular sciences2026

Differential Expression of Cytotoxic-Associated Markers in Circulating CD4

Julio Sesma-Soto, Mariana Patlán, Rashidi Springall, Araceli Páez, Felipe Massó, Luis H Silveira, Luis M Amezcua-Guerra

Abstract read
In one paragraph

Article in International journal of molecular sciences, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Julio Sesma-SotoDepartment of Immunology, Instituto Nacional de Cardiología Ignacio Chávez, Mexico City 14080, Mexico.ORCID 0009-0007-3301-1338
Mariana PatlánBasic Research Subdirectorate, Instituto Nacional de Cardiología Ignacio Chávez, Mexico City 14080, Mexico.ORCID 0000-0002-6660-7388
Rashidi SpringallDepartment of Immunology, Instituto Nacional de Cardiología Ignacio Chávez, Mexico City 14080, Mexico.
Araceli PáezUNAM/INC Translational Research Unit, Instituto Nacional de Cardiología Ignacio Chávez, Mexico City 14080, Mexico.
Felipe MassóUNAM/INC Translational Research Unit, Instituto Nacional de Cardiología Ignacio Chávez, Mexico City 14080, Mexico.ORCID 0000-0001-8671-3367
Luis H SilveiraDepartment of Rheumatology, Instituto Nacional de Cardiología Ignacio Chávez, Mexico City 14080, Mexico.
Luis M Amezcua-GuerraDepartment of Immunology, Instituto Nacional de Cardiología Ignacio Chávez, Mexico City 14080, Mexico.ORCID 0000-0002-6258-5732

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Rheumatoid arthritis (RA) involves alterations in cytotoxic lymphoid differentiation, yet the precise phenotypic remodeling of circulating helper T cells and natural killer (NK) cells remains incompletely understood. We evaluated circulating CD4

Indexed as

Arthritis, RheumatoidCD28 AntigensCD4-Positive T-LymphocytesKiller Cells, NaturalAdultAgedBiomarkersFas Ligand ProteinFemaleGranzymesHumansMiddle AgedPerforinBiomarkersCD28 AntigensFas Ligand ProteinGranzymesPerforinCD4+CD28− cellscytotoxicityFas ligandgranzyme Bimmune senescenceperforinrheumatoid arthritis

Identifiers

PMID42883779
PMCPMC13665205

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.