Evidence map›Paper›PMID 42883759›Full record

ReviewInternational journal of molecular sciences2026

Genetic Predisposition and Infidelity: From Molecular Variation to Relationship Behavior-A Narrative Review.

Ana Karina Zambrano

Abstract readReview
In one paragraph

Review in International journal of molecular sciences, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

1 author.

Ana Karina ZambranoCentro de Investigación Genética y Genómica, Facultad de Ciencias de la Salud Eugenio Espejo, Universidad UTE, Quito 170129, Ecuador.ORCID 0000-0003-4102-3965

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Trust and pair bonding are central to human social life, and their violation through infidelity carries a measurable psychological cost. Whether individual differences in such behavior are partly genetic remains contested, because the available evidence combines heterogeneous phenotypes with candidate gene designs of limited statistical power. This narrative review synthesizes genetic evidence on infidelity, pair bonding, responses to trust violation and indirect traits such as novelty seeking, grading it by evidentiary strength. Twin modeling of extrapair mating yields broad-sense heritability of approximately 62% in men and 40% in women, but this specific estimate has not been reproduced in a comparable sample and describes population variance, not individual causation. Reported associations for

Indexed as

Genetic Predisposition to DiseaseGenetic VariationSexual BehaviorDopamine Plasma Membrane Transport ProteinsFemaleHumansMaleMonoamine OxidaseReceptors, Dopamine D4Receptors, OxytocinReceptors, VasopressinTrustAVPR1A protein, humanDopamine Plasma Membrane Transport ProteinsDRD4 protein, humanMonoamine Oxidasemonoamine oxidase A, humanOXTR protein, humanReceptors, Dopamine D4Receptors, OxytocinReceptors, VasopressinSLC6A3 protein, humanbehavioraldopamine D4extramarital relationsgene–environment interactiongeneticsmonoamine oxidaseoxytocinpair bondvasopressin

Identifiers

PMID42883759
PMCPMC13664871

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.