Evidence map›Paper›PMID 42883757›Full record

ReviewInternational journal of molecular sciences2026

Interstitial Ion Regulation in Cognitive Fatigability and Delayed Recovery: A Hypothesis-Driven Critical Review.

Hiromu Monai

Abstract readReview
In one paragraph

Review in International journal of molecular sciences, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

1 author.

Hiromu MonaiInstitute of Human Life Sciences, Ochanomizu University, Bunkyo-ku 112-8610, Tokyo, Japan.ORCID 0000-0002-6975-7218

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Cognitive fatigability is the time-dependent destabilization of cognitive performance under sustained demand and is distinct from subjective fatigue. Neurophysiological effects may persist after demand. To link performance instability during demand with delayed recovery, this non-systematic, hypothesis-driven Review focuses on the extracellular milieu, which reflects and shapes neural activity. This Review operationally defines the interstitial ionic state as extracellular K

Indexed as

CognitionFatigueIonsAnimalsAstrocytesBrainExtracellular SpaceHumansNeuronsPotassiumIonsPotassiumastrocytebrain fatiguecognitive fatigabilitydelayed recoveryextracellular ion homeostasisextracellular potassiuminterstitial ionic statenon-synaptic signaling

Identifiers

PMID42883757
PMCPMC13665452

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.