Evidence map›Paper›PMID 42883695›Full record

SynthesisInternational journal of molecular sciences2026

MicroRNA Responses Associated with Vector-Borne Diseases in Humans and Arthropod Vectors: A Systematic Review.

Tilini K De Silva, John Stenos, Stephen R Graves, Tarka R Bhatta, Nathan B Unsworth, Ryan J Farr, Cameron R Stewart, Simon M Firestone

Abstract readSystematic ReviewReview
PubMed Full text at PMC Publisher
In one paragraph

Synthesis in International journal of molecular sciences, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Tilini K De SilvaDepartment of Veterinary Biosciences, Melbourne Veterinary School, Faculty of Science, The University of Melbourne, Parkville, VIC 3052, Australia.ORCID 0000-0002-0631-2705
John StenosAustralian Rickettsial Reference Laboratory, University Hospital, Geelong, VIC 3220, Australia.ORCID 0000-0001-5465-2926
Stephen R GravesAustralian Rickettsial Reference Laboratory, University Hospital, Geelong, VIC 3220, Australia.ORCID 0000-0002-8204-0924
Tarka R BhattaAustralian Rickettsial Reference Laboratory, University Hospital, Geelong, VIC 3220, Australia.ORCID 0000-0002-8199-8444
Nathan B UnsworthSensors and Effectors Division, Defence Science and Technology Group, 506 Lorimer Street, Fisherman's Bend, Melbourne, VIC 3207, Australia.
Ryan J FarrCSIRO Health & Biosecurity, Australian Centre for Disease Preparedness, Geelong, VIC 3220, Australia.ORCID 0000-0003-1636-1815
Cameron R StewartCSIRO Health & Biosecurity, Australian Centre for Disease Preparedness, Geelong, VIC 3220, Australia.ORCID 0000-0002-3395-7859
Simon M FirestoneDepartment of Veterinary Biosciences, Melbourne Veterinary School, Faculty of Science, The University of Melbourne, Parkville, VIC 3052, Australia.ORCID 0000-0002-3239-1419

Funding

Australian Rickettsial Reference Laboratory N/AThe University of Melbourne Research Higher Degree project support
6 · The paper itself

Abstract

Vector-borne diseases (VBDs) represent a significant public health challenge. Early and accurate diagnosis is crucial for effective disease management and control, with host-encoded microRNAs (miRNAs) emerging as promising disease biomarkers. This systematic review surveys research conducted on miRNA responses in disease vectors and human hosts of VBDs. A systematic search of four databases and manual searching identified 93 qualifying articles. Numerous VBDs were described, with the most common focus on dengue (21%;

Indexed as

Arthropod VectorsMicroRNAsVector Borne DiseasesAnimalsBiomarkersHumansTicksBiomarkersMicroRNAsbiomarkersdifferential expressionmicroRNAmiRNAsmosquitoessystematic reviewticksvector-borne diseasesvectors

Identifiers

PMID42883695
PMCPMC13664826

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.