Evidence map›Paper›PMID 42883301›Full record

ArticleMolecules (Basel, Switzerland)2026

Bacterial Adhesion on Orthopedic Titanium Implants Coated with Silver-Doped Hydroxyapatite and Chitosan.

Urška Filipović, Anamarija Zore, Nives Matijaković Mlinarić, Anže Abram, Roman Štrukelj, Martina Modic, Andreja Leskovac, Sandra Petrović, Vojislav Stanić, Safia Dahmen and 2 more

Abstract read
In one paragraph

Article in Molecules (Basel, Switzerland), 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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0cells of the map it votes in
0citing papers in PubMed
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1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Urška FilipovićFaculty of Health Sciences, University of Ljubljana, 1000 Ljubljana, Slovenia.
Anamarija ZoreFaculty of Health Sciences, University of Ljubljana, 1000 Ljubljana, Slovenia.ORCID 0000-0003-1920-2983
Nives Matijaković MlinarićFaculty of Health Sciences, University of Ljubljana, 1000 Ljubljana, Slovenia.ORCID 0000-0002-3751-1790
Anže AbramJozef Stefan Institute, 1000 Ljubljana, Slovenia.ORCID 0000-0001-8702-4715
Roman ŠtrukeljFaculty of Health Sciences, University of Ljubljana, 1000 Ljubljana, Slovenia.
Martina ModicJozef Stefan Institute, 1000 Ljubljana, Slovenia.
Andreja LeskovacVinča Institute of Nuclear Sciences-National Institute of the Republic of Serbia, University of Belgrade, 11351 Belgrade, Serbia.ORCID 0000-0002-6293-5237
Sandra PetrovićVinča Institute of Nuclear Sciences-National Institute of the Republic of Serbia, University of Belgrade, 11351 Belgrade, Serbia.ORCID 0000-0003-0930-6455
Vojislav StanićVinča Institute of Nuclear Sciences-National Institute of the Republic of Serbia, University of Belgrade, 11351 Belgrade, Serbia.ORCID 0000-0001-9714-3769
Safia DahmenLaboratory of Transmissible Diseases and Biologically Active Substances LR99ES27, Faculty of Pharmacy, University of Monastir, Monastir 5000, Tunisia.ORCID 0009-0002-4165-4695
Raja Gošnak DahmaneFaculty of Health Sciences, University of Ljubljana, 1000 Ljubljana, Slovenia.
Klemen BohincFaculty of Health Sciences, University of Ljubljana, 1000 Ljubljana, Slovenia.ORCID 0000-0003-2126-8762

Funding

The Slovenian Research and Innovation Agency P3-0388
6 · The paper itself

Abstract

Orthopedic site infections remain a growing concern in implantology, particularly in light of rising antibiotic resistance. Identifying optimal, standardized antimicrobial treatments is increasingly challenging. Beyond the design and functional properties of orthopedic materials, key factors such as bacterial adhesion and genotoxicity must also be considered. To develop implant materials with enhanced antibacterial properties and biocompatibility, this study investigated titanium (Ti) surfaces coated with chitosan (CS) and silver-doped hydroxyapatite (AgHA) at weight ratios of 1:1, 1:2, and 2:1. The incorporation of silver ions into hydroxyapatite demonstrated potent antibacterial activity, achieving a greater than 99% reduction in

Indexed as

Bacterial AdhesionChitosanCoated Materials, BiocompatibleDurapatiteProstheses and ImplantsSilverTitaniumAnti-Bacterial AgentsHumansStaphylococcus aureusSurface PropertiesAnti-Bacterial AgentsChitosanCoated Materials, BiocompatibleDurapatiteSilverTitaniumbacterial adhesionchitosansilver-doped hydroxyapatitetitanium implants

Identifiers

PMID42883301
PMCPMC13667199

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.