Evidence map›Paper›PMID 42883220›Full record

ReviewMolecules (Basel, Switzerland)2026

Recent Advances in Polysaccharides from

Gang Wang, Han Di, Xinxin Chen, Yanhong Wang, Feng Guan

Abstract readReview
In one paragraph

Review in Molecules (Basel, Switzerland), 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Gang WangSchool of Pharmacy, Heilongjiang University of Chinese Medicine, Harbin 150040, China.ORCID 0009-0004-7792-476X
Han DiSchool of Pharmacy, Heilongjiang University of Chinese Medicine, Harbin 150040, China.
Xinxin ChenSchool of Pharmacy, Heilongjiang University of Chinese Medicine, Harbin 150040, China.
Yanhong WangSchool of Pharmacy, Heilongjiang University of Chinese Medicine, Harbin 150040, China.
Feng GuanSchool of Pharmacy, Heilongjiang University of Chinese Medicine, Harbin 150040, China.ORCID 0009-0004-7234-1135

Funding

Heilongjiang Touyan Innovation Team Program [2019] No.5
6 · The paper itself

Abstract

ethnopharmacological relevanceAIM OF THE REVIEW: This review aims to offer a systematic summary of the recent progress in the extraction, purification, detailed structural characteristics, and various pharmacological activities of SFP. It further explores the structure-activity relationships and toxicological profiles, thereby laying a solid foundation for the future development and utilization of SFP in pharmaceutical applications. MATERIALS AND

methodsKey terms including "

resultsModern extraction methodologies, including ultrasound-assisted, enzyme-assisted, and microwave-assisted extraction, significantly enhance SFP yield and preserve bioactivity compared to conventional hot-water extraction. Structurally, SFP are highly heterogeneous macromolecules predominantly composed of glucose, galactose, arabinose, and xylose. The diverse biological activities of SFP are heavily dependent on their structure-activity relationships; notably, targeted chemical modifications like sulfation drastically amplify their receptor affinity and efficacy. Pharmacologically, SFP exhibit potent antioxidant, anti-inflammatory, immunomodulatory, antitumor, and hepatoprotective properties by modulating core cellular signaling pathways such as NF-κB and Nrf2, while maintaining a highly favorable safety and cytocompatibility profile.

Indexed as

Plant ExtractsPolysaccharidesSophoraSophora flavescensAnimalsHumansMedicine, Chinese TraditionalStructure-Activity RelationshipPlant ExtractsPolysaccharidesextractionpharmacological activitySophora flavescens polysaccharidesstructural characteristicstructure-activity relationship

Identifiers

PMID42883220
PMCPMC13666048

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.