Effects of Colostrum-Period Fecal Microbiota Transplantation on Growth Performance, Immune Function and Gut Microbiota in Pre-Weaned Calves.

Jingkun Zhang, Yaning Sun, Xintong Li, Duo You, Zhanhe Zhang, Ming Xu, Donglin Wu

Abstract read

In one paragraph

Article in Animals : an open access journal from MDPI, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it

0cells of the map it votes in

0citing papers in PubMed

–field-weighted citation impact

1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Jingkun ZhangCollege of Animal Science, Inner Mongolia Agricultural University, Hohhot 010018, China.

Yaning SunCollege of Animal Science, Inner Mongolia Agricultural University, Hohhot 010018, China.

Xintong LiCollege of Animal Science, Inner Mongolia Agricultural University, Hohhot 010018, China.

Duo YouCollege of Animal Science, Inner Mongolia Agricultural University, Hohhot 010018, China.

Zhanhe ZhangCollege of Animal Science, Inner Mongolia Agricultural University, Hohhot 010018, China.ORCID 0009-0006-9971-5824

Ming XuCollege of Animal Science, Inner Mongolia Agricultural University, Hohhot 010018, China.ORCID 0000-0002-0816-7046

Donglin WuCollege of Animal Science, Inner Mongolia Agricultural University, Hohhot 010018, China.ORCID 0000-0003-2194-5129

Funding

the Natural Science Foundation of Inner Mongolia Autonomous Region 2023LHMS03048

6 · The paper itself

Abstract

Neonatal calf diarrhea caused by intestinal microbial dysbiosis severely restricts rearing efficiency, and fecal microbiota transplantation (FMT) emerges as a promising antibiotic-free strategy for regulating gut homeostasis. Nevertheless, to the best of our knowledge, the effects of colostrum-period FMT and the functional differences between colonic and colostrum delivery routes remain poorly characterized in pre-weaned dairy calves. We hypothesized that colostrum-period FMT would accelerate gut microbiota maturation, improve immune status and reduce diarrhea incidence in pre-weaned calves, with delivery-route-dependent effects. This study aimed to investigate how two colostrum-phase FMT delivery routes shape growth performance, serum immune profiles and gut microbiota in neonatal Holstein calves. Sixty newborn calves were randomly assigned to three groups (

Indexed as

average daily gaindiarrhea incidenceFMT administration routeIgGInterleukin

Identifiers

PMID42883057

DOI10.3390/ani16193088

PMCPMC13663452

What OpenQuestion holds

Textmetadata

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.