ArticleAnimals : an open access journal from MDPI2026
Single-Step Genomic Reaction Norm and ssGWAS Reveal Heat-Load-Dependent Genetic Architecture of Age at Puberty in Yorkshire Gilts.
Article in Animals : an open access journal from MDPI, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Abstract
Heat stress adversely affects porcine reproduction, but genetic variation in the response of age at puberty (AP) to heat exposure remains poorly characterized in gilts. We analyzed 4438 AP records from Yorkshire gilts using adjusted meteorological data and compared three heat-exposure gradients across five prepubertal windows. Pedigree- and single-step genomic reaction-norm models were fitted, followed by single-step genome-wide association analyses of the intercept and slope. Among the 15 exposure scenarios, the best-fitting model used the proportion of sustained heat-stress days in the 14-day window before first observed estrus; a one-standard-deviation increase in this measure was associated with a 7.64-day increase in AP. Both reaction-norm models detected significant genetic variance for environmental sensitivity (
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