Stage-Specific Associations Between Respiratory Pathogens and Mortality in Sheep: A Multivariate Analysis.

Antonio Romero-Salmoral, Manuela Hernández-García, Francisco Javier Navas González, Carmen Tarradas Iglesias, Belen Huerta Lorenzo, Inmaculada Luque Moreno, Eva Boyer-Bustamante, Francisco Jurado-Martos

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In one paragraph

Article in Animals : an open access journal from MDPI, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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0citing papers in PubMed

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1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

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3 · Its place in the literature

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0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

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5 · Who and what money

Authors and funding

8 authors.

Antonio Romero-SalmoralAnimal Health Research Group: Diagnosis and Control of Diseases (SANDYC), Unidad de Investigación Competitiva (UIC) Zoonosis y Enfermedades Emergentes ENZOEM, Department of Animal Health, International Excellence Agrifood Campus 'CeiA3', University of Córdoba, 14071 Córdoba, Córdoba, Spain.ORCID 0009-0001-8516-8384

Manuela Hernández-GarcíaDepartment of I+D+I, Centro Tecnológico de Investigación Agroalimentaria (CICAP), 14400 Pozoblanco, Córdoba, Spain.

Francisco Javier Navas GonzálezDepartment of Genetics, International Excellence Agrifood Campus 'CeiA3', University of Córdoba, 14071 Córdoba, Córdoba, Spain.

Carmen Tarradas IglesiasAnimal Health Research Group: Diagnosis and Control of Diseases (SANDYC), Unidad de Investigación Competitiva (UIC) Zoonosis y Enfermedades Emergentes ENZOEM, Department of Animal Health, International Excellence Agrifood Campus 'CeiA3', University of Córdoba, 14071 Córdoba, Córdoba, Spain.

Belen Huerta LorenzoAnimal Health Research Group: Diagnosis and Control of Diseases (SANDYC), Unidad de Investigación Competitiva (UIC) Zoonosis y Enfermedades Emergentes ENZOEM, Department of Animal Health, International Excellence Agrifood Campus 'CeiA3', University of Córdoba, 14071 Córdoba, Córdoba, Spain.ORCID 0000-0002-1110-7722

Inmaculada Luque MorenoAnimal Health Research Group: Diagnosis and Control of Diseases (SANDYC), Unidad de Investigación Competitiva (UIC) Zoonosis y Enfermedades Emergentes ENZOEM, Department of Animal Health, International Excellence Agrifood Campus 'CeiA3', University of Córdoba, 14071 Córdoba, Córdoba, Spain.ORCID 0000-0003-1838-2636

Eva Boyer-BustamanteInternational Doctoral School in Agri-Food (eidA3), Rabanales University Campus, University of Cordoba, 14071 Córdoba, Córdoba, Spain.ORCID 0009-0001-4278-8209

Francisco Jurado-MartosDepartment of I+D+I, Centro Tecnológico de Investigación Agroalimentaria (CICAP), 14400 Pozoblanco, Córdoba, Spain.

Funding

European Union "NextGenerationEU"/PRTR MCIN/AEI/10.13039/501100011033Ricardo Delgado Vizcaíno Foundation 12023007

6 · The paper itself

Abstract

Ovine Respiratory Complex (ORC) is a major cause of lamb mortality in intensive and semi-intensive sheep production systems. Its multifactorial etiology, involving bacterial and viral pathogens together with host and environmental factors, complicates disease control and limits the effectiveness of conventional preventive measures. Although respiratory pathogens are commonly detected in healthy lambs, their contribution to mortality at different production stages remains poorly understood. This study evaluated the relationships between respiratory pathogens and lamb mortality using canonical multivariate analysis. A total of 200 bronchoalveolar lavage samples were collected from apparently healthy lambs aged 50-60 days during winter (n = 80) and summer (n = 120) on 10 commercial sheep farms in southwestern Spain. Samples were analyzed by real-time PCR for the detection of major bacterial and viral respiratory pathogens, and mortality records from farms and feedlots during 2022-2023 were incorporated into the analysis. A high herd-level prevalence was detected for

Indexed as

bronchoalveolar lavageMannheimia haemolyticaMesomycoplasma ovipneumoniaePasteurella multocidareal-time PCR

Identifiers

PMID42882998

DOI10.3390/ani16193028

PMCPMC13663387

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.