Evidence map›Paper›PMID 42882939›Full record

ReviewCancers2026

Mapping Integrative Decision-Making Frameworks in Advanced Cancer Care: A Scoping Review of Diagnostic, Supportive-Care, and Therapeutic Integration.

Kazuyuki Murase, Yusuke Sugama, Yohei Arihara, Kohichi Takada, Kunihiko Ishitani

Abstract readReview
In one paragraph

Review in Cancers, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Kazuyuki MuraseDivision of Medical Oncology, Department of Internal Medicine, Sapporo Medical University School of Medicine, S-1 W-16, Chuo-ku, Sapporo 060-8543, Hokkaido, Japan.ORCID 0000-0003-2642-8665
Yusuke SugamaHigashi Sapporo Hospital, 3-3-7-35 Higashi Sapporo, Shiroishi-ku, Sapporo 003-8585, Hokkaido, Japan.ORCID 0000-0003-2899-0512
Yohei AriharaDivision of Medical Oncology, Department of Internal Medicine, Sapporo Medical University School of Medicine, S-1 W-16, Chuo-ku, Sapporo 060-8543, Hokkaido, Japan.
Kohichi TakadaDivision of Medical Oncology, Department of Internal Medicine, Sapporo Medical University School of Medicine, S-1 W-16, Chuo-ku, Sapporo 060-8543, Hokkaido, Japan.ORCID 0000-0002-1393-9442
Kunihiko IshitaniHigashi Sapporo Hospital, 3-3-7-35 Higashi Sapporo, Shiroishi-ku, Sapporo 003-8585, Hokkaido, Japan.ORCID 0000-0001-8420-1608

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

BACKGROUND/

objectivesDecision-making in advanced cancer care is intertwined with diagnostic profiling, prognostic communication, supportive care, and anticancer treatment selection. An author-developed D-S-T × B/C/E conceptual mapping scaffold-three decision/action domains (Diagnosis, Supportive care, Therapy) and three evaluative dimensions (Biological, Clinical, Existential)-was used to organise the literature, to identify coverage gaps and recurring framework categories, and, as a secondary conceptual synthesis objective, to derive a candidate integrative framework.

methodsThe review was conducted according to the Joanna Briggs Institute (JBI) methodology for scoping reviews, pre-registered on OSF, and reported per PRISMA-ScR. PubMed was searched on 21 June 2026, and the final evidence set was derived solely from this search. Eligible records concerning adults with advanced cancer were dual-screened and charted using a structured form.

resultsEighty-two records (2010-2026) were included. Under the strict D-S-T × B/C/E matrix, Supportive care showed the highest joint coverage, particularly S × C (59/82, 72.0%), whereas D × B and D × E were the least represented cells (13/82 each, 15.9%). Eight recurring framework categories were inductively derived from the charted framework descriptors, led by early integrated palliative care (30/82) and prognosis-informed shared decision-making (27/82). Twenty-two records met an emergence-candidate screen defined at the synthesis stage, of which three received the maximum cross-axis coupling score of 6/6 from both reviewers.

conclusionsThe advanced-cancer decision-framework literature clusters around a small number of architectures with uneven D-S-T × B/C/E coverage. Diagnosis-centred frameworks coupled with biological or existential dimensions were relatively under-represented within our mapping and represent priority targets for future primary research; the proposed Adaptive framework provides one structure in which this research could be conducted.

Indexed as

advanced canceranticancer treatmentCFIRpalliative carePRISMA-ScRprognostic communicationscoping reviewshared decision-making

Identifiers

PMID42882939
PMCPMC13664350

What OpenQuestion holds

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Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.