Evidence map›Paper›PMID 42882903›Full record

ReviewCancers2026

Intensive Care in Patients with Solid Tumours: A Practical Framework for Integrated Onco-Critical Care.

Alicia Castelo-Loureiro, Amanda Lesmes González de Aledo, Mateo Bover Larroya, Zaira Molina Collado, Cristina Serrano Gómez, Isaías Martín Badía, Jesús González Olmedo, Santiago Terán, Marcos Valiente Fernández, Carlos Heredia-Mena and 6 more

Abstract readReview
In one paragraph

Review in Cancers, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

16 authors.

Alicia Castelo-LoureiroDepartment of Medical Oncology, Hospital Universitario 12 de Octubre, 28041 Madrid, Spain.ORCID 0000-0001-6075-2173
Amanda Lesmes González de AledoDepartment of Intensive Care Medicine, Hospital Universitario 12 de Octubre, 28041 Madrid, Spain.ORCID 0000-0001-8397-4844
Mateo Bover LarroyaDepartment of Medical Oncology, Hospital Universitario 12 de Octubre, 28041 Madrid, Spain.ORCID 0000-0001-6628-3777
Zaira Molina ColladoDepartment of Intensive Care Medicine, Hospital Universitario 12 de Octubre, 28041 Madrid, Spain.ORCID 0009-0004-3060-462X
Cristina Serrano GómezDepartment of Medical Oncology, Hospital Universitario 12 de Octubre, 28041 Madrid, Spain.ORCID 0009-0009-2710-6423
Isaías Martín BadíaDepartment of Intensive Care Medicine, Hospital Universitario 12 de Octubre, 28041 Madrid, Spain.ORCID 0000-0002-7024-1331
Jesús González OlmedoDepartment of Internal Medicine, Hospital Universitario 12 de Octubre, 28041 Madrid, Spain.ORCID 0000-0003-3858-7508
Santiago TeránDepartment of Medical Oncology, Hospital Universitario 12 de Octubre, 28041 Madrid, Spain.ORCID 0009-0006-7027-3110
Marcos Valiente FernándezHospital Ruber Juan Bravo, 28006 Madrid, Spain.ORCID 0000-0002-0533-6211
Carlos Heredia-MenaDepartment of Internal Medicine, Hospital Universitario 12 de Octubre, 28041 Madrid, Spain.ORCID 0000-0002-3719-6233
Joseph Exebio-JaraDepartment of Medical Oncology, Hospital Universitario 12 de Octubre, 28041 Madrid, Spain.ORCID 0009-0002-4401-4239
Lidia Orejón GarcíaDepartment of Intensive Care Medicine, Hospital Universitario 12 de Octubre, 28041 Madrid, Spain.
María Carnevali FríasDepartment of Intensive Care Medicine, Hospital Universitario 12 de Octubre, 28041 Madrid, Spain.
Carlos Gómez MartínDepartment of Medical Oncology, Hospital Universitario 12 de Octubre, 28041 Madrid, Spain.
María Cruz Martín DelgadoDepartment of Intensive Care Medicine, Hospital Universitario 12 de Octubre, 28041 Madrid, Spain.
Luis Paz-AresDepartment of Medical Oncology, Hospital Universitario 12 de Octubre, 28041 Madrid, Spain.ORCID 0000-0002-1947-3364

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The number of patients with solid tumours requiring intensive care is increasing as cancer survival improves and oncological treatments become more complex. Intensive care unit (ICU) admission decisions should not be based on cancer diagnosis, metastatic status or palliative treatment intent alone. This narrative review presents a practical, multidisciplinary framework for assessing critically ill patients with solid tumours. It integrates acute illness severity and reversibility, organ failure, baseline performance status and frailty, cancer trajectory, remaining treatment options, expected functional recovery and patient preferences. We discuss contemporary anticancer treatment toxicities, cancer-associated thromboembolic disease, older adults, palliative care, communication and ethical decision-making. We also propose an algorithm ranging from full ICU support to a time-limited ICU trial with predefined reassessment or comfort-focused care. Early joint assessment by oncology and intensive care teams, followed by dynamic reassessment, may reduce both inappropriate escalation and premature exclusion from potentially beneficial organ support. Future research should prioritize structured pathways, improved prognostic tools and outcomes beyond survival, including functional recovery, quality of life and the ability to resume meaningful cancer treatment.

Indexed as

critical illnessfrailtyintensive care unitmultidisciplinary careonco-critical carepalliative caresolid tumourstime-limited ICU trial

Identifiers

PMID42882903
PMCPMC13664010

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.