Evidence map›Paper›PMID 42882824›Full record

ArticleCancers2026

circSCAF11 Attenuates TGF-β/SMAD2/3 Signaling to Suppress Colorectal Cancer Progression.

Ling He, Bin Liu, Zhaoyong Li

Abstract read
In one paragraph

Article in Cancers, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Ling HeHunan Research Center of the Basic Discipline for Cell Signaling, College of Biology, Hunan University, Changsha 410082, China.
Bin LiuHunan Research Center of the Basic Discipline for Cell Signaling, College of Biology, Hunan University, Changsha 410082, China.
Zhaoyong LiHunan Research Center of the Basic Discipline for Cell Signaling, College of Biology, Hunan University, Changsha 410082, China.ORCID 0000-0002-1502-4027

Funding

Natural Science Foundation of Hunan 2026JJ50573
6 · The paper itself

Abstract

Circular RNAs with high stability offer potential advantages for developing therapeutic agents against cancers. CircSCAF11 has been reported to be downregulated in CRC, yet its functional mechanisms remain largely unknown. In this study, we demonstrate that circSCAF11 is a genuine circular RNA generated by back-splicing of exon 5 of the

Indexed as

apoptosiscircSCAF11colorectal cancerEMTTGF-β signaling pathway

Identifiers

PMID42882824
PMCPMC13664225

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.