ArticleMaterials (Basel, Switzerland)2026
Surface Morphology Control and Amino Functionalization of Silicon Nanoparticles for Enhanced Antibody Immobilization.
Article in Materials (Basel, Switzerland), 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Abstract
The large specific surface area of nanoparticles makes them an attractive platform for antibody immobilization in immunoassays, but the combined effects of their surface structuring and chemical functionalization on properties relevant to antibody immobilization have not yet been clarified. Here, porous and spiky silicon nanoparticles (SiNPs) were fabricated by metal-assisted chemical etching, and the relationships among specific surface area, amino functionalization, and the JT-95-related ELISA signal following BS3-mediated immobilization were investigated. The formation of the porous and spiky surface structures was confirmed by scanning electron microscopy, including quantitative image analysis, and nitrogen adsorption analysis revealed that the specific surface area increased from 62.3 m
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