Evidence map›Paper›PMID 42882483›Full record

ArticleCells2026

Patient-Derived iPSC Modeling Reveals Dysregulation of the Mucin-Type O-Glycan Biosynthesis-Related Transcriptional Program in

Jing Hao, Zhengye Zhao, Shuang Li, Di Liu, Guozhuang Li, Lin Wang, Jingyi Xie, Zhifa Zheng, Jianguo Zhang, Zhihong Wu and 2 more

Abstract read
In one paragraph

Article in Cells, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Jing HaoDepartment of Orthopedic Surgery, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences & Peking Union Medical College, Beijing 100730, China.
Zhengye ZhaoDepartment of Orthopedic Surgery, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences & Peking Union Medical College, Beijing 100730, China.
Shuang LiStem Cell Facility, National Infrastructures for Translational Medicine, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences & Peking Union Medical College, Beijing 100730, China.
Di LiuDepartment of Orthopedic Surgery, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences & Peking Union Medical College, Beijing 100730, China.ORCID 0000-0002-5803-7223
Guozhuang LiDepartment of Orthopedic Surgery, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences & Peking Union Medical College, Beijing 100730, China.
Lin WangDepartment of Orthopedic Surgery, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences & Peking Union Medical College, Beijing 100730, China.
Jingyi XieDepartment of Orthopedic Surgery, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences & Peking Union Medical College, Beijing 100730, China.
Zhifa ZhengState Key Laboratory of Complex Severe and Rare Diseases, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences & Peking Union Medical College, Beijing 100730, China.ORCID 0009-0007-8265-3724
Jianguo ZhangDepartment of Orthopedic Surgery, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences & Peking Union Medical College, Beijing 100730, China.ORCID 0000-0003-3129-5190
Zhihong WuStem Cell Facility, National Infrastructures for Translational Medicine, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences & Peking Union Medical College, Beijing 100730, China.
Nan WuDepartment of Orthopedic Surgery, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences & Peking Union Medical College, Beijing 100730, China.ORCID 0000-0002-9429-2889
Lina ZhaoState Key Laboratory of Complex Severe and Rare Diseases, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences & Peking Union Medical College, Beijing 100730, China.

Funding

Beijing Municipal Science and Technology Commission No. Z251100004625001Beijing Natural Science Foundation 7254401CAMS Innovation Fund for Medical Sciences 2024-I2M-TS-002CAMS Innovation Fund for Medical Sciences 2025-I2M-XHJC-002CAMS Innovation Fund for Medical Sciences 2025-I2M-XHXX-020China National Center for Biotechnology Development 2023YFC2507700In-dependent Research Fund of the State Key Laboratory of Complex, Severe, and Rare Diseas-es NO. 2025-I-PY-006National High Level Hospital Clinical Research Funding 2025-PUMCH-A-115National Natural Science Foundation of China 82402760Peking Union Medical College Hospital No. ULJ11240The Fundamental Research Funds for the Central Universities, Peking Union Medical Col-lege 3332025114The Strategic Research and Consulting Project of the Chinese Academy of Engineering 2024-ZCQ-18
6 · The paper itself

Abstract

TBX6-associated congenital scoliosis (TACS) is a genetic subtype of congenital scoliosis caused by reduced

Indexed as

Induced Pluripotent Stem CellsModels, BiologicalMucinsPolysaccharidesScoliosisT-Box Domain ProteinsTranscription, GeneticCell DifferentiationChondrogenesisHumansN-AcetylgalactosaminyltransferasesOsteogenesisMucinsN-AcetylgalactosaminyltransferasesPolysaccharidesT-Box Domain ProteinsTBX6 protein, humancongenital scoliosisinduced pluripotent stem cellsmucin-type O-glycan biosynthesisosteochondral differentiationTBX6

Identifiers

PMID42882483
PMCPMC13664113

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.