Evidence map›Paper›PMID 42882232›Full record

ArticleDiagnostics (Basel, Switzerland)2026

Analytical and Biological Factors Associated with Oncogenic Variant Yield in Tumor-Agnostic Plasma ctDNA Profiling.

Stephen George, Lavanya Ranganathan, Yizhen Xiang, Alexander Malt, Shashwat Sahay, Eva-Maria Mayr, Florian Scherer, Hanno Glimm, Stefan Fröhling, Naveed Ishaque and 3 more

Abstract read
In one paragraph

Article in Diagnostics (Basel, Switzerland), 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors.

Stephen GeorgeGerman Cancer Consortium (DKTK) Partner Site Berlin and German Cancer Research Center (DKFZ), 69120 Heidelberg, Germany.ORCID 0000-0001-8639-9857
Lavanya RanganathanGerman Cancer Consortium (DKTK) Partner Site Freiburg and German Cancer Research Center (DKFZ), 69120 Heidelberg, Germany.
Yizhen XiangBerlin Institute of Health at Charité - Universitätsmedizin Berlin, Center of Digital Health, 10117 Berlin, Germany.ORCID 0009-0002-3444-7081
Alexander MaltBerlin Institute of Health at Charité - Universitätsmedizin Berlin, Center of Digital Health, 10117 Berlin, Germany.ORCID 0009-0005-4049-0846
Shashwat SahayBerlin Institute of Health at Charité - Universitätsmedizin Berlin, Center of Digital Health, 10117 Berlin, Germany.
Eva-Maria MayrInstitute of Pathology, School of Medicine and Health, Technical University of Munich (TUM), 81675 Munich, Germany.
Florian SchererGerman Cancer Consortium (DKTK) Partner Site Freiburg and German Cancer Research Center (DKFZ), 69120 Heidelberg, Germany.
Hanno GlimmDepartment of Translational Medical Oncology, National Center for Tumor Diseases (NCT), NCT/University Cancer Center Dresden, a Partnership Between German Cancer Research Center (DKFZ), Faculty of Medicine and University Hospital Carl Gustav Carus, Dresden University of Technology (TUD), and Helmholtz-Zentrum Dresden-Rossendorf, 01307 Dresden, Germany.
Stefan FröhlingDivision of Translational Medical Oncology, German Cancer Research Center (DKFZ), 69120 Heidelberg, Germany.ORCID 0000-0001-7907-4595
Naveed IshaqueBerlin Institute of Health at Charité - Universitätsmedizin Berlin, Center of Digital Health, 10117 Berlin, Germany.ORCID 0000-0002-8426-901X
Nicole PfarrInstitute of Pathology, School of Medicine and Health, Technical University of Munich (TUM), 81675 Munich, Germany.ORCID 0000-0002-5977-5375
Damian T RiekeGerman Cancer Consortium (DKTK) Partner Site Berlin and German Cancer Research Center (DKFZ), 69120 Heidelberg, Germany.ORCID 0000-0003-0027-7977
Ingeborg TinhoferGerman Cancer Consortium (DKTK) Partner Site Berlin and German Cancer Research Center (DKFZ), 69120 Heidelberg, Germany.ORCID 0000-0002-0512-549X

Funding

German Cancer Research Center (DKFZ)
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

ctDNA burdenliquid biopsyplasma sequencingprecision oncologytumor heterogeneity

Identifiers

PMID42882232
PMCPMC13664594

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.