Evidence map›Paper›PMID 42881921›Full record

ReviewJournal of clinical medicine2026

Multimodality Imaging of Mitral Regurgitation.

Angelo Squeri, Valeria Maria De Luca, Stefano Censi, Carmine Pizzi, Luca Bergamaschi, Nicole Suma, Nicola Forzati, Rita Conti

Abstract readReview
In one paragraph

Review in Journal of clinical medicine, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Angelo SqueriUO Cardiologia, IRCCS Maria Cecilia Hospital, Care & Research, 48033 Cotignola, Italy.ORCID 0000-0001-9115-5443
Valeria Maria De LucaUO Cardiologia, IRCCS Maria Cecilia Hospital, Care & Research, 48033 Cotignola, Italy.ORCID 0009-0005-3276-3373
Stefano CensiUO Cardiologia, IRCCS Maria Cecilia Hospital, Care & Research, 48033 Cotignola, Italy.ORCID 0000-0002-9893-3508
Carmine PizziDepartment of Medical and Surgical Sciences (DIMEC), Alma Mater Studiorum-University of Bologna, 40138 Bologna, Italy.ORCID 0000-0002-4048-675X
Luca BergamaschiDepartment of Medical and Surgical Sciences (DIMEC), Alma Mater Studiorum-University of Bologna, 40138 Bologna, Italy.ORCID 0000-0001-8186-9717
Nicole SumaUO Cardiologia, IRCCS Maria Cecilia Hospital, Care & Research, 48033 Cotignola, Italy.ORCID 0009-0003-6119-8890
Nicola ForzatiUO Cardiologia, IRCCS Maria Cecilia Hospital, Care & Research, 48033 Cotignola, Italy.
Rita ContiUO Cardiologia, IRCCS Maria Cecilia Hospital, Care & Research, 48033 Cotignola, Italy.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Mitral regurgitation is one of the most common valvular heart diseases and requires an accurate diagnostic approach to define its etiology, mechanism, severity, and therapeutic implications. This review analyzes the integrated role of the main cardiovascular imaging modalities in the assessment of mitral regurgitation. Transthoracic echocardiography (TTE) represents the first-line imaging modality, providing a dynamic assessment of valve anatomy, ventricular function, and hemodynamic consequences, whereas transesophageal echocardiography (TEE) provides complementary high-resolution anatomical characterization. Cardiac magnetic resonance provides accurate quantification of ventricular volumes, the regurgitant volume and fraction, and myocardial remodeling and is particularly useful when echocardiographic findings are inconclusive or discordant. Computed tomography, owing to its high spatial resolution, offers detailed information on the mitral apparatus, annulus, calcifications, and anatomical relationships, supporting the planning of surgical and transcatheter procedures. The integration of echocardiography, CMR, and CT enables more comprehensive risk stratification and personalized treatment selection. The review highlights how multimodality imaging is now essential for guiding the diagnostic and therapeutic pathway, improving intervention timing, the procedural choice, and the overall management of patients with mitral regurgitation.

Indexed as

cardiac magnetic resonancecomputed tomographyechocardiographymitral regurgitationmultimodality imaging

Identifiers

PMID42881921
PMCPMC13666139

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.