ArticleHealthcare (Basel, Switzerland)2026
Psychological Distress, Somatic Symptom Burden, and Quality of Life in Rheumatoid Arthritis: A Cross-Sectional Study in Bosnia and Herzegovina.
Article in Healthcare (Basel, Switzerland), 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Abstract
backgroundRheumatoid arthritis (RA) affects physical and psychological well-being, but Southeast European evidence is limited.
methodsThis cross-sectional study included 85 consecutive adults with RA at a tertiary rehabilitation center. Participants completed Bosnian translations of the PHQ-9, GAD-7, PHQ-15, Brief Symptom Inventory, and MANSA. Same-day assessment included pain VAS, DAS28-CRP(3), and HAQ-DI. Continuous scores were analyzed using 20 Spearman correlations with FDR adjustment and four exploratory MANSA models with HC3-robust standard errors. Four internally discordant GSI records were excluded from primary GSI analyses (
resultsMean DAS28-CRP(3), HAQ-DI, and MANSA scores were 5.31, 1.69, and 4.37. MANSA correlated with PHQ-9 (rho = -0.49), GAD-7 (-0.30), PHQ-15 (-0.37), and GSI (-0.53; all q ≤ 0.016). PHQ-15 correlated with pain (rho = 0.36) and HAQ-DI (0.31), PHQ-9 correlated with HAQ-DI (0.25), and GSI correlated with pain and HAQ-DI (both 0.28; all q < 0.05). Adjusted MANSA associations remained (standardized beta = -0.49 to -0.24; all q < 0.05), with conclusions unchanged when all GSI values were included.
conclusionsHigher symptom scores were associated with poorer quality of life. Findings are exploratory and do not establish diagnostic or causal relationships.
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