Evidence map›Paper›PMID 42881559›Full record

ReviewThe Kaohsiung journal of medical sciences2026

Harnessing Artificial Intelligence to Predict Dental Crowding in Modern Orthodontic Practice: A Comprehensive Review.

Xiwen Xin, Shun-Yu Kan, Tianle Chen, Ching-Chang Ko

Abstract readReview
In one paragraph

Review in The Kaohsiung journal of medical sciences, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Xiwen XinDivision of Orthodontics, The Ohio State University College of Dentistry, Columbus, Ohio, USA.
Shun-Yu KanDivision of Orthodontics, The Ohio State University College of Dentistry, Columbus, Ohio, USA.
Tianle ChenDepartment of Computer Science, Boston University, Boston, Massachusetts, USA.
Ching-Chang KoDivision of Orthodontics, The Ohio State University College of Dentistry, Columbus, Ohio, USA.ORCID https://orcid.org/0000-0001-7245-4480

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Dental crowding is fundamental to orthodontic diagnosis and treatment planning, yet what constitutes "crowding" remains surprisingly heterogeneous. Space analysis quantifies tooth size-arch length discrepancy, irregularity indices characterize alignment displacement, and clinician-assigned severity reflects broader diagnostic interpretation. This narrative review examines the evolution of crowding assessment from conventional space analysis and digital measurement to two-dimensional artificial intelligence (AI), three-dimensional point-cloud learning, and clinician-aware agentic AI. Digitalization improves efficiency and reproducibility but does not resolve fundamental dependencies on how crowding is defined, anatomically represented, and established as a reference standard. Two-dimensional models enable prediction from readily available images but are constrained by projection and scale, whereas three-dimensional approaches directly learn from dental surface representations and can capture local geometric relationships. In a companion study of 495 arches from 284 patients, PointNet++ achieved an R

Indexed as

artificial intelligencedental crowdingdigital orthodonticsintraoral scanningPointNet++

Identifiers

PMID42881559
PMCPMC13672865

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.