Evidence map›Paper›PMID 42881411›Full record

ReviewMicrobial cell factories2026

Effective bio-activities of the metal nanoparticles mycosynthesized by the plants' fungal endophytes.

Adel K Madbouly, Younes M Rashad

Abstract readReview
In one paragraph

Review in Microbial cell factories, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Adel K MadboulyMicrobiology Department, Faculty of Science, University of Ain Shams, Cairo, Egypt. adel_ramadan@sci.asu.edu.eg.
Younes M RashadPlant Protection and Biomolecular Diagnosis Department, Arid Lands Cultivation Research Institute (ALCRI), City of Scientific Research and Technological Applications (SRTA-city), New Borg El-Arab City, Egypt.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Fungal endophytes act as bio-nano factories and are favored over bacteria and plant extracts, as they secrete large quantities of proteins and enzymes, facilitating stable, efficient, and economic nanoparticle synthesis. This review highlights the advantages of plant-associated fungal endophytes as bio-factories for metal nanoparticles (MNPs) synthesis and critically examines the biological activities and potential applications of these MNPs in human health, food technology, and agriculture. Compared to chemical synthesis, biogenic MNPs are more resistant to aggregation due to the involvement of different biomolecules, including secondary metabolites, enzymes, and proteins, reducing the metal ions to form MNPs. Biosynthesis of MNPs by several fungal genera, such as Fusarium spp., Penicillium spp., and Aspergillus spp., enables alleviation of the undesirable cytotoxicity and increased stability. In the food industry, MNPs play substantial roles in inhibiting browning and preventing food contamination. In agriculture, they act as herbicides, fungicides, pesticides, and plant growth promoters. Field application trials of these MNPs are recommended before their manipulation as a control strategy. In medicine, MNPs behave as antimicrobials, drug-delivery, antioxidants, and anticancer agents. They are applied in ophthalmology to facilitate drug delivery onto the site of infection via the improvement of targeted delivery. MNPs have demonstrated anticancer potency against cancer cell lines; however, they may also display cytotoxicity against the normal cells, especially at small sizes. However, at low pH, release of Ag

Indexed as

EndophytesFungiMetal NanoparticlesPlantsAnti-Infective AgentsAntineoplastic AgentsHumansAnti-Infective AgentsAntineoplastic AgentsAnticancer activityAntimicrobialsEndophytic fungiGreen synthesisNanotechnologySustainable agriculture

Identifiers

PMID42881411
PMCPMC13670673

What OpenQuestion holds

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Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.