Evidence map›Paper›PMID 42881281›Full record

ArticleJournal of orofacial orthopedics = Fortschritte der Kieferorthopadie : Organ/official journal Deutsche Gesellschaft fur Kieferorthopadie2026

Pain assessment using prostaglandin E

Navia Jose Paul, Haritha Pottipalli Sathyanarayana, Vignesh Kailasam

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Article in Journal of orofacial orthopedics = Fortschritte der Kieferorthopadie : Organ/official journal Deutsche Gesellschaft fur Kieferorthopadie, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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1 · What the graph read from it

What it found

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2 · The registry

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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

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4 · The record

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5 · Who and what money

Authors and funding

3 authors.

Navia Jose PaulSri Ramachandra Institute of Higher Education and Research, Porur, India.
Haritha Pottipalli SathyanarayanaSri Ramachandra Institute of Higher Education and Research, Porur, India. haritha.ps@sriramachandra.edu.in.
Vignesh KailasamSri Ramachandra Institute of Higher Education and Research, Porur, India.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveTo evaluate pain differences using prostaglandin (PGE MATERIALS AND

methodsTwenty-two eligible patients were randomized 1:1 to PSLA or CFA groups. Both arches were bonded with 0.022-inch appliances. A 0.014-inch Damon CuNiTi archwire was used in the PSLA group, while a 0.014-inch CuNiTi ovoid archwire was used in the CFA group. Gingival crevicular fluid from the distal gingival sulcus of the maxillary right canine and VAS scores were recorded at five time points: 1 h before archwire insertion (T0), and 24 (T1), 48 (T2), 72 (T3), and 168 h (T4) after insertion. Longitudinal changes were analyzed using generalized estimating equation (GEE) models with group, time, and group × time interaction effects. Data were expressed as median and interquartile range (IQR).

resultsPGE

conclusionBoth PSLA and CFA demonstrated similar temporal patterns in PGE

Indexed as

Biochemical markersGingival crevicular fluidInflammatory mediatorsOrthodontic tooth movementVisual analog scale

Identifiers

PMID42881281

What OpenQuestion holds

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.