Evidence map›Paper›PMID 42880913›Full record

Trial reportBeijing da xue xue bao. Yi xue ban = Journal of Peking University. Health sciences2026

[Short-term clinical outcomes of complete dentures fabricated by conventional and CAD/CAM milling techniques: A self-controlled study with randomized wearing sequence].

Hui Cao, Kaiqi Qin, Xu Zhang, Hu Chen, Yuchun Sun, Xuemei Bao, Yongsheng Zhou

Abstract readRandomized Controlled TrialEnglish AbstractComparative Study
In one paragraph

Trial report in Beijing da xue xue bao. Yi xue ban = Journal of Peking University. Health sciences, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

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5 · Who and what money

Authors and funding

7 authors.

Hui CaoStomatological College, Inner Mongolia Medical University, Hohhot 010051, China.
Kaiqi QinInstitute of Medical Technology, Peking University Health Science Center, Beijing 100191, China.
Xu ZhangCenter of Digital Dentistry, Peking University School and Hospital of Stomatology & National Center of Stomatology & National Clinical Research Center for Oral Diseases & National Engineering Laboratory for Digital and Material Technology of Stomatology & Beijing Key Laboratory of Intelligent Biomanufacturing and Regeneration for Craniofacial Tissues & Beijing Key Laboratory of Digital Stomatology, Beijing 100081, China.
Hu ChenCenter of Digital Dentistry, Peking University School and Hospital of Stomatology & National Center of Stomatology & National Clinical Research Center for Oral Diseases & National Engineering Laboratory for Digital and Material Technology of Stomatology & Beijing Key Laboratory of Intelligent Biomanufacturing and Regeneration for Craniofacial Tissues & Beijing Key Laboratory of Digital Stomatology, Beijing 100081, China.
Yuchun SunInstitute of Medical Technology, Peking University Health Science Center, Beijing 100191, China.
Xuemei BaoDepartment of Prosthodontics, Affiliated Hospital of Inner Mongolia Medical University, Hohhot 010050, China.
Yongsheng ZhouInstitute of Medical Technology, Peking University Health Science Center, Beijing 100191, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveTo preliminarily compare the short-term clinical outcomes of conventional and computer-aided design/computer-aided manufacturing (CAD/CAM) monolithic milled complete dentures and to provide clinical evidence for selecting a digital complete-denture fabrication technique.

methodsSeven edentulous patients were enrolled in a self-controlled study with a randomized wearing sequence. Each participant received one conventionally fabricated complete denture and one CAD/CAM monolithic milled complete denture. The fabrication technique was not actively disclosed before subjective assessment. A 2-week washout period, during which the participants wore their previous dentures, separated the two wearing periods. Subjective visual analogue scale (VAS) scores for overall satisfaction, mandibular denture retention, masticatory function, mucosal comfort, speech, and esthetics, together with pressure-point count, objective mandibular retention force, and objective masticatory efficiency, were assessed at insertion, 1 week, and 1 month. Within-patient comparisons between the two techniques were performed at each time point. Overall satisfaction, pressure-point count, objective retention force, and objective masticatory efficiency were additionally analyzed using a 2×3 fully within-subject repeated-measures analysis of variance (ANOVA), followed by Bonferroni-adjusted post hoc comparisons.

resultsSignificant between-process differences in satisfaction, aesthetics, retention VAS, mastication VAS, and pressure point counts were found over three time points (all

conclusionIn this small, short-term, within-patient study with a randomized wearing sequence, CAD/CAM monolithic milled complete dentures showed advantages in several patient-reported outcomes, objective mandibular retention force, and objective masticatory efficiency at 1 week and 1 month. These advantages did not extend to all outcomes or time points, and the between-technique difference in pressure-point count narrowed over time.

Indexed as

Computer-Aided DesignDenture, CompleteDenture DesignAgedFemaleHumansMaleMiddle AgedPatient SatisfactionComplete dentureComputer-aided design/computer-aided manufacturing(CAD/CAM)Digital prosthodonticsSelf-controlled study

Identifiers

PMID42880913
PMCPMC13672157

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.